Changes in blood flow linked to obesity start in the early stages of Cushing’s disease, as evidenced by a significant decrease in the blood-pumping ability of the heart, a new study reported. While obese patients appeared to have normal heart function in standard echocardiographic examinations, a noninvasive method called…
A rare type of nasal tumor, called olfactory neuroblastoma, caused ectopic Cushing’s syndrome in a 47-year-old man, as described in a recent case report. Surgical treatment led to a reduction of the patient’s blood cortisol and adrenocorticotropic hormone (ACTH) levels, which were elevated as a result of the tumor. “This…
Ubie and the Cushing’s Support and Research Foundation (CSRF) have teamed up to raise awareness and shorten the time people with Cushing’s syndrome have to wait for a diagnosis. The long-term collaboration seeks to confirm the diagnostic capacity of Ubie’s free, artificial intelligence (AI)-powered platform called Symptom…
Cushing’s Awareness Day is April 8, and the Cushing’s community is gearing up with events and fundraising efforts to spread awareness and raise money to combat the disorder. In celebration of this year’s Awareness Day, Xeris Pharmaceuticals, which markets Cushing’s treatment Recorlev (levoketoconazole), is teaming up with the…
A Phase 3 trial testing the oral medication relacorilant in people with Cushing’s syndrome caused by adrenal adenoma, a type of adrenal gland tumor, or adrenal hyperplasia, a condition in which the adrenal glands become enlarged, has finished enrolling participants. Relacorilant’s developer, Corcept Therapeutics, said 137 participants have…
A timely diagnosis of Cushing’s syndrome during pregnancy, along with appropriate individualized treatment, is critical for minimizing complications for the mother and the child, according to a case series study that followed five pregnant women with Cushing’s caused by adrenal tumors at a hospital in China. “By implementing a multidisciplinary…
A 40-year-old man who developed ectopic Cushing’s syndrome as a result of a lung tumor remained undiagnosed for years, despite showing Cushing’s symptoms and progressive physical and mental decline, a recent case study shows. Once he was diagnosed, surgery to remove the tumor resulted in his health improving substantially.
Endoscopic transsphenoidal surgery (ETSS), a type of minimally invasive surgery to remove pituitary tumors through the nose, was found to be safe and effective for bringing about remission in Cushing’s disease, according to a study in Turkey. In patients in whom tumors were larger and had spread into the…
Doctors should suspect Cushing’s syndrome when they see patients with purple stretch marks and metabolic conditions such as diabetes, even if those symptoms aren’t the reasons for a medical visit, physicians in Japan wrote in a case study describing how they reached that diagnosis for a woman in her early…
Individuals with Cushing’s syndrome have a greater buildup of fat around the heart and inside the coronary arteries — the blood vessels that supply blood to the heart — compared with people who don’t have the condition but who are at a higher risk of developing cardiovascular disease, according to…
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