Catarina Silva, MSc,  —

More than 25 percent of women with Cushing’s disease experienced their first symptoms within one year of giving birth, a small study by the Pacific Neuroscience Institute found. The findings suggest a possible causal relationship between the biological stress of pregnancy and Cushing’s disease (CD), with more than a two-fold…

A precise form of radiation therapy, known as Gamma Knife radiosurgery, produces a low rate of adverse radiation effects and provides good tumor control when used as an upfront treatment strategy in Cushing’s disease patients, an international study suggests. The study, “Upfront Gamma Knife radiosurgery for…

In Cushing’s disease (CD), depression is correlated with body image distortion and lower self-esteem, according to an Indian study. Physicians should be attentive to symptoms of mental disturbances in CD patients to provide them a better prognosis. The research, “A Study on Psychiatric Disorders, Body Image…

The Endocrine Society has selected 13 leaders in the endocrinology field as winners of its prestigious 2019 Laureate Awards. Among the recipients is James W. Findling, MD, an expert in Cushing’s disease. Each recipient will be presented with the award at ENDO 2019,…

OvaScience and Millendo Therapeutics will merge in an all-stock deal to push forward Millendo’s lead candidates livoletide (AZP-531) and nevanimibe (ATR-101) for the treatment of Prader-Willi syndrome and Cushing’s syndrome, respectively. An investor group that includes New Enterprise Associates, Frazier Healthcare Partners, Roche…

A test using betamethasone — a corticosteroid that causes the pituitary gland to stop producing ACTH – can accurately predict short- and long-term remission in Cushing’s disease patients who have had pituitary surgery, a retrospective study reports. The research, “An early post-operative ACTH suppression test can safely predict short- and long-term…

American and Dutch patients with Cushing’s syndrome have different ways of interpreting the same items on a disease-specific quality-of-life (QoL) questionnaire, research shows. The study, “Assessing Differences in How the CushingQoL Is Interpreted Across Countries: Comparing Patients From the U.S. and the Netherlands,” was published in…

Metformin, an oral type 2 diabetes medicine, can promote cell death in tumors that cause Cushing’s disease and reduce the excessive production of the adrenocorticotroph hormone (ACTH) that underlies it, a study in mice cells reports. These findings suggest that metformin, a tablet, may offer a new way of treating…