News

Isturisa managed severe Cushing’s due to advanced adrenal cancer

A 70-year-old woman in the U.S. with Cushing’s syndrome due to advanced adrenal gland cancer who was effectively managed with Isturisa (osilodrostat) was the subject of a report by researchers. After the woman developed adrenal insufficiency, which is when the adrenal glands become unable to produce sufficient amounts of…

Woman’s glucocorticoid-induced Cushing’s syndrome misdiagnosed

A woman developed therapy-related Cushing’s syndrome after prolonged treatment with a glucocorticoid for osteoarthritis, which is marked by joint damage and degeneration, a case study reports. As a result, the woman developed adrenal insufficiency and was misdiagnosed with perimenopause. In adrenal insufficiency, the adrenal glands become unable to produce sufficient…

Weight loss, low potassium mark unusual Cushing’s disease case

A 75-year-old woman with Cushing’s disease who was first seen with marked weight loss and low blood levels of potassium, or hypokalemia, was described by researchers as an unusual example of the condition, one otherwise resembling ectopic Cushing’s syndrome. “This case highlights the need to entertain a broad differential…

Removal of 1 affected adrenal gland effective in some Cushing’s cases

Surgical removal of one cancerous adrenal gland resulted in disease remission after six months in nearly half of people with Cushing’s syndrome due to tumors in both adrenal glands — a condition known as primary bilateral macronodular adrenal hyperplasia, or PBMAH. That’s according to data from a study in China…

Diabetes, high blood pressure in pregnancy may signal Cushing’s

Doctors in England missed signs of Cushing’s syndrome in a 26-year-old woman with gestational diabetes and high blood pressure, a case researchers said highlights the need for heightened awareness and vigilance, particularly in pregnant women with those conditions. “The diagnosis of [Cushing’s syndrome] in pregnancy is not straightforward due to…

Cushing’s syndrome linked to liver fat buildup: Study

High levels of cortisol in the bloodstream of people with Cushing’s syndrome were directly linked to significant metabolic abnormalities leading to the buildup of fat deposits in the liver, according to a new study from researchers in China. The researchers noted that liver fat accumulation increases a person’s risk of…