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Cushing’s symptoms secondary to tumor ease with Isturisa

A young woman who developed Cushing’s syndrome three years after being diagnosed with a metastatic neuroendocrine tumor saw her cortisol levels decrease and Cushing’s-related symptoms ease after being treated with Isturisa (osilodrostat). The woman, 27, was started on hydrocortisone when here cortisol levels fell to lower than normal values,…

Symptoms worsen with increasing cortisol levels in Cushing’s disease

People with Cushing’s disease may have higher levels of cortisol and more severe symptoms than those with other forms of Cushing’s, according to a recent study in Turkey. “The severity of disease symptoms worsens with increasing cortisol levels,” researchers wrote. The study, “Metabolic, hormonal profiles and comorbidities in…

Minimally invasive surgery may be effective for Cushing’s: Study

Partial adrenalectomy, or the removal of only a portion of the adrenal gland containing a tumor instead of the entire gland, using a minimally invasive procedure is safe and feasible in people with Cushing’s syndrome and other conditions, according to a study in Germany. The procedure, called posterior retroperitoneoscopic partial…

Disease symptoms, surgery outcomes vary with patient age

Older Cushing’s disease patients less frequently present classical symptoms of the disease, and have more coexistent conditions and larger tumors than those who develop the disease at a younger age. That’s according to a study that analyzed patients at several sites in the U.S. who underwent surgery to…

Thyroid cancer causes Cushing’s syndrome in man in his 30s

A rare and aggressive form of thyroid cancer caused Cushing’s syndrome in a man in his 30s, according to a case report. “This case underscores the complexity of diagnosing and managing ectopic Cushing’s syndrome, particularly when it is secondary to a rare malignancy,” researchers wrote. The case report, “…