An imaging technique that uses a radioactive tracer to find pituitary tumors causing Cushing’s disease showed limited and inconsistent results in a small pilot study. Of the 10 adults with newly diagnosed or persistent/recurrent Cushing’s disease, two had positive results on the scan, called 68Ga-pentixafor PET/MRI. Only one result…
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Women with adrenal Cushing’s syndrome may have lower muscle mass than those with Cushing’s disease, a study in China suggests. Researchers found that premenopausal women with Cushing’s caused by a type of adrenal tumor called an adenoma had significantly lower muscle mass relative to their height…
Editor’s note: This story mentions suicide. If you or someone you know needs help, the national suicide and crisis lifeline in the U.S. is available by calling or texting 988. There is also an online chat at 988lifeline.org. Internationally, find a suicide prevention helpline at findahelpline.com. Living with…
The case of a teenage girl who developed drug-induced Cushing’s syndrome after long-term use of a very potent corticosteroid ointment was described in a recent report. The researchers noted that Cushing’s caused by topical corticosteroids has been reported before, but most pediatric cases have involved infants and young children. This…
The interaction between two proteins may play a role in Cushing’s disease tumors, potentially signaling a new approach to treatment, a study found. The PPP1R17 protein may help pituitary tumors that cause Cushing’s grow by blocking the activity of another protein, PP2A. Gilenya (fingolimod), a treatment approved in…
An experimental device designed to continuously measure cortisol and help diagnose and manage cortisol-related disorders, including Cushing’s disease, received breakthrough device designation from the U.S. Food and Drug Administration (FDA). The designation is intended for medical devices that may provide more effective diagnosis or treatment for life-threatening or irreversibly…
The U.S. Food and Drug Administration (FDA) has granted orphan drug designation to Lundbeck’s asedebart, a designation that may provide incentives for the development of this experimental antibody for endogenous Cushing’s syndrome. A Phase 2 trial is currently underway in people with Cushing’s disease, one form of the…
A study tied high cortisol in Cushing’s disease to an increase in certain blood cells not explained by the presence of the disease-causing tumor, suggesting that simple blood tests may help doctors monitor patients and their response to treatment. “Routine complete blood counts may serve as accessible biomarkers for…
People with Cushing’s disease often do an unusual amount of eating at night — but this behavior is driven mainly by mental health challenges and sleep disturbances, not because of the hormonal imbalance that underlies the disease. That’s according to a study, “Night…
Asedebart, an experimental treatment designed to ease symptoms in Cushing’s disease and other forms of endogenous Cushing’s syndrome, has been granted orphan drug status in the European Union. That designation, awarded to the Lundbeck therapy by the European Commission, aims to incentivize the development of treatments for rare…
Recent Posts
- The blood tests that help me monitor my Cushing’s disease
- Scan misses some Cushing’s disease tumors in small pilot study
- Most of my life with Cushing’s disease is spent in the ‘in-between’
- Women with adrenal Cushing’s may have lower muscle mass, study finds
- As my mental health declines, I’m reaching out for help
- Uncontrollable Cushing’s weight gain can shatter a woman’s body image
- Maintaining a romantic relationship with a provider of intimate care
- Long-term topical steroid use linked to Cushing syndrome in adolescent
- Getting vaccinated takes a toll on me as someone with Cushing’s disease
- Protein interaction could point to new Cushing’s treatment approach