A woman in her early 30s who developed severe ectopic Cushing’s syndrome due to a small thymus tumor was effectively managed with medications to reduce cortisol levels followed by surgery, according to a case report from Poland. After the initial surgery, the patient experienced two recurrences of Cushing’s within seven…
A woman in Switzerland with metastatic lung cancer who developed thin skin and was later diagnosed with Cushing’s syndrome was the subject of a repoort by researchers. Metastatic cancer occurs when the disease has spread from its original site to other parts of the body. In this case, Cushing’s was…
A young woman with Cushing’s disease and acromegaly — marked by the abnormal growth of certain body parts due to pituitary gland dysfunction — saw her symptoms ease after undergoing surgery to remove a large hormone-producing tumor that caused both rare conditions, a study from Bangladesh reported. “The…
People with Cushing’s disease who have more education are also more likely to have better patient outcomes — including longer survival — than those with lower educational levels, a study in Sweden found. According to the study, which followed individuals with Cushing’s for as long as 20 years before…
A 71-year-old man with Cushing’s disease developed avascular necrosis in the hips and shoulders, a condition in which bone tissue dies due to lack of blood supply, a U.S. case study reports. His Cushing’s symptoms, including avascular necrosis in the hips, were successfully managed with surgery to remove the…
A young woman who developed Cushing’s syndrome three years after being diagnosed with a metastatic neuroendocrine tumor saw her cortisol levels decrease and Cushing’s-related symptoms ease after being treated with Isturisa (osilodrostat). The woman, 27, was started on hydrocortisone when here cortisol levels fell to lower than normal values,…
People with Cushing’s disease may have higher levels of cortisol and more severe symptoms than those with other forms of Cushing’s, according to a recent study in Turkey. “The severity of disease symptoms worsens with increasing cortisol levels,” researchers wrote. The study, “Metabolic, hormonal profiles and comorbidities in…
Partial adrenalectomy, or the removal of only a portion of the adrenal gland containing a tumor instead of the entire gland, using a minimally invasive procedure is safe and feasible in people with Cushing’s syndrome and other conditions, according to a study in Germany. The procedure, called posterior retroperitoneoscopic partial…
Older Cushing’s disease patients less frequently present classical symptoms of the disease, and have more coexistent conditions and larger tumors than those who develop the disease at a younger age. That’s according to a study that analyzed patients at several sites in the U.S. who underwent surgery to…
Long-term treatment with relacorilant led to a sustained decrease in blood pressure, blood sugar levels, and body weight in people with Cushing’s syndrome, new data from an extension study shows. The extension study (NCT03604198) is assessing relacorilant’s long-term safety and efficacy in 116 people with Cushing’s who completed…
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