News

Surprising data found in study on Cushing’s disease in children

More boys were diagnosed with Cushing’s disease before puberty than were girls, according to an examination of medical records of children and adolescent patients across Turkey. These findings contrast with observations made in adults, in whom women are diagnosed with Cushing’s far more often than men. The researchers noted,…

Case study: Unusual Cushing’s symptoms after woman’s childbirth

A 31-year-old woman exhibited unusual symptoms of Cushing’s disease following childbirth, but didn’t show some of the disease’s hallmark features, such as weight gain and fat accumulation. The woman’s atypical symptoms, which included psychosis and severe muscle weakness, were accompanied by a challenging clinical course that led ultimately…

Rare case of Cushing’s caused by CRH-secreting thyroid tumor

For a man in Denmark, Cushing’s syndrome developed as a result of a medullary thyroid carcinoma — a tumor that formed in the thyroid gland in the neck and released corticotropin-releasing hormone (CRH), a hormone that triggers cortisol production. During the workup, however, results of inferior petrosal sinus sampling,…

Changes in brain circuitry may underlie anxiety, cognitive issues

People with Cushing’s disease have differences in brain activity that significantly associate with the severity of cognitive and mental health symptoms, implying such changes in brain activity may give rise to these symptoms. That’s according to the recent study “Dynamic functional connectivity changes associated with psychiatric traits and…

Pituitary tumor surgery found safe, effective in elderly patients

Surgery to remove a tumor in the brain’s pituitary gland is effective in patients 75 years or older, including those with Cushing’s disease, and is associated with a low rate of complications, according to a study in France. The surgery was generally performed using a minimally invasive procedure and…