Marisa Wexler, MS, senior science writer —

People with Cushing’s disease are at an increased risk of complications, particularly psychiatric disorders requiring hospitalization, even after the disease-causing tumor has been surgically removed, a study indicates. Its findings “support the need for comprehensive clinical evaluation and tailored interventions for [Cushing’s disease] patients, even post-surgery,” the researchers wrote.

Analyzing the gene activity profile of blood cells may help detect Cushing’s syndrome and could be useful in assessing its severity, a recent study reports. The study, “Whole blood transcriptomic signature of Cushing’s syndrome,” was published in the European Journal of Endocrinology. Cushing’s syndrome is an umbrella…

Daily meditation with the help of headband that tracks brain activity and serves as a personal meditation coach may help people with Cushing’s syndrome have less pain and a better experience while recovering from surgery. That’s according to new research presented at the Endocrine Society Annual Meeting (ENDO 2024) in…

People with Cushing’s syndrome have an increased risk of venous thromboembolism (VTE), that is, dangerous blood clots that obstruct the normal flow of blood through veins, but most treatment centers don’t have standard procedures for reducing VTE risk in Cushing’s patients, a study indicates. “A specific thromboprophylaxis protocol for patients…

Cushing’s Awareness Day is April 8, and the Cushing’s community is gearing up with events and fundraising efforts to spread awareness and raise money to combat the disorder. In celebration of this year’s Awareness Day, Xeris Pharmaceuticals, which markets Cushing’s treatment Recorlev (levoketoconazole), is teaming up with the…

A Phase 3 trial testing the oral medication relacorilant in people with Cushing’s syndrome caused by adrenal adenoma, a type of adrenal gland tumor, or adrenal hyperplasia, a condition in which the adrenal glands become enlarged, has finished enrolling participants. Relacorilant’s developer, Corcept Therapeutics, said 137 participants have…

An interaction between an anti-inflammatory steroid and an anti-fungal medication led to the onset of Cushing’s syndrome and reduced adrenal gland function in a man being treated for complications from a bone marrow transplant. A case report on the 67-year-old man’s symptoms highlights possibly serious consequences from these medicines’…

A rare adrenal tumor turned out to be the cause of a man’s Cushing’s syndrome, according to a case report from China. The man had severe metabolic complications related to Cushing’s, but these resolved rapidly following surgical removal of the disease-driving tumor, called a pheochromocytoma. Diagnosing and managing a pheochromocytoma…

Nearly one out of four people with difficult-to-treat type 2 diabetes also has Cushing’s syndrome, according to preliminary data from the Phase 4 CATALYST clinical trial. “These results are very powerful,” Ralph DeFronzo, MD, an investigator on the CATALYST study and professor of medicine at UT Health San Antonio,…

Singapore’s Health Sciences Authority (HSA) has issued a warning that Gu Jie Ling, an herbal concoction marketed as a “traditional medicine,” contains a drug called dexamethasone that can cause Cushing’s syndrome, and has advised the public not to purchase or consume it. The HSA recommends that people who have…