Mutations in the USP8 gene appear to switch on a signaling pathway, called Sonic Hedgehog (SHH), in pituitary tumors that cause Cushing’s disease, according to a study involving patient tumor data and laboratory cell experiments. These results suggest that targeting this pathway could help guide future treatment research for patients…
After an unrelated medical exam revealed a mass on a man’s right adrenal gland, further testing showed his symptoms were actually caused by Cushing’s disease, rooted in a small pituitary tumor in the brain, according to a case report. The case highlights the need for careful testing to find…
Discussion
The term “flare-up” is used to describe the sudden onset of aggravated symptoms. Although I’m medicated for Cushing’s disease, I still have significant flare-ups. Often, they’ll happen when I overexert myself, fail to rely on my mobility aids, or overestimate how good I feel. I also have flare-ups during…
Becoming educated and informed about Cushing’s disease is a good first step. Here you’ll find general information such as the diagnosis, symptoms, and causes.
It helps to know others have been where you are now. Here’s a collection of our columnists’ words of wisdom to help you along on your Cushing’s journey.
Besides surgery, there are several therapeutic strategies that may be used to manage Cushing’s disease. Here you can find more information about some of the approved and experimental treatments.
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