Lindsey Shapiro, PhD,  science writer—

Lindsey earned her PhD in neuroscience from Emory University in Atlanta, where she studied novel therapeutic strategies for treatment-resistant forms of epilepsy. She was awarded a fellowship from the American Epilepsy Society in 2019 for this research. Lindsey also previously worked as a postdoctoral researcher, studying the role of inflammation in epilepsy and Alzheimer’s disease.

Articles by Lindsey Shapiro

People with Cushing’s show ‘paradoxical’ immune profile: Study

People with Cushing’s syndrome, including those with Cushing’s disease, exhibit immune system alterations that could contribute to some symptoms of the disease, a small study suggests. Analyses of immune cells from Cushing’s patients indicated signs of both systemic (whole body) inflammation as well as immunosuppression, which scientists believe might…

Isturisa found to successfully treat ectopic Cushing’s in woman, 69

Isturisa (osilodrostat) was found to successfully treat Cushing’s syndrome associated with a hormone-producing tumor in the lungs in a 69-year-old woman with lung cancer, according to a recent case study. The woman simultaneously underwent cancer treatment with Tagrisso (osimertinib), which also was successful. The researchers noted that this case…

Cushing’s syndrome cause of osteoporosis in young woman

Cushing’s syndrome should be considered when osteoporosis, or weak bones, are found in young adults, scientists in China reported. They described treating a 26-year-old woman who came to their clinic with chronic back pain that X-rays identified as due to multiple bone fractures, and who exhibited a number of other…

Severe Infection and Electrolyte Imbalances May Signal Cushing’s

A severe muscle infection and electrolyte imbalances were among clinical signs leading to a Cushing’s syndrome diagnosis in an 82-year-old woman, according to a recent case report. The patient also showed other cardiovascular risk factors for Cushing’s that aided clinicians in their diagnosis. Infectious complications after a surgery caused the…

Metopirone Available to Treat Endogenous Cushing’s in Colombia

Adults and children with endogenous Cushing’s syndrome in Colombia will have access to Metopirone (metyrapone), the first Cushing’s treatment to be approved in the country, HRA Pharma Rare Diseases, which developed and markets the treatment, announced. With this registration, Colombia joins several other countries, including in Europe, the…

Long-term Recorlev Found Safe, Effective for Endogenous Cushing’s

Long-term treatment with Recorlev (levoketoconazole) safely leads to sustained reductions in cortisol levels, disease signs and symptoms, and improvements in quality of life in adults with endogenous Cushing’s syndrome, according to nearly two years of data from the Phase 3 SONICS trial. Treatment benefits were generally maintained or deepened…