A malignant tumor of the thymus, a small organ in the upper chest that plays a critical role in the immune system, was identified as the cause of Cushing’s syndrome in a 43-year-old man, according to a recent U.K. case report. After surgery to remove the thymus, the condition was…
Researchers have identified ceritinib, a cancer medication, as a promising treatment candidate for Cushing’s disease after successfully using miniature, lab-grown pituitary tumors, known as organoids, to test its effectiveness. Ceritinib, marketed as Zykadia to treat certain lung cancers, effectively inhibited tumor growth and reduced the tumor-driven excess of adrenocorticotropic…
About half of people with Cushing’s disease have abnormalities in their adrenal glands, the small organs above the kidneys that make cortisol, a new study from Israel has found. Further, small growths in the adrenal tissue — called adrenal nodules — occurred about 10 times more often in these…
A 52‑year‑old woman who came to the hospital complaining of chest pain and difficulty breathing was found to have both lung cancer and Cushing’s syndrome. Researchers said the cancer caused the Cushing’s, a rare occurrence that shows the need for “a coordinated, multidisciplinary approach” to managing complex sets of symptoms.
People with endogenous Cushing’s syndrome face a higher risk of cancer compared with the general population, and are twice as likely to develop cancers within 10 years of their diagnosis, according to a new study from Israel. Being 60 or older, male, or having adrenal Cushing’s — a form of…
Early screening and treatment for possible underlying causes of obesity, such as Cushing’s disease, before a weight-loss procedure called bariatric surgery may help prevent mismanaging the condition and improve patient outcomes. That’s according to a report that described the case of a man in Iraq who developed complications and…
Sequential treatment with ketoconazole to lower cortisol levels and octreotide to help keep cortisol under control may be effective as a treatment for a subset of people with mild Cushing’s disease, according to a study from the Netherlands. Two of the three patients who responded to treatment, reflected…
Low-dose aspirin, an antiplatelet agent used to reduce blood clotting, may be better than enoxaparin, the current gold standard, at preventing thromboses in people with Cushing’s syndrome, a U.S. study found. Compared with those on enoxaparin, a form of low-molecular weight heparin (LMWH), patients who took low-dose aspirin had a…
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