Patricia Inácio, PhD, science writer —

A 31-year-old woman exhibited unusual symptoms of Cushing’s disease following childbirth, but didn’t show some of the disease’s hallmark features, such as weight gain and fat accumulation. The woman’s atypical symptoms, which included psychosis and severe muscle weakness, were accompanied by a challenging clinical course that led ultimately…

Etomidate helped normalize dangerously high cortisol levels in a woman with Cushing’s syndrome who had an adrenal gland tumor before she having surgery to remove it, a recent case report shows. “In its severe form, Cushing’s syndrome is a medical emergency that must be rapidly controlled. Etomidate is both safe…

A newborn girl with a rare genetic disorder called McCune-Albright syndrome (MAS) developed Cushing’s syndrome, according to researchers in Turkey. While Cushing’s syndrome in the context of MAS is linked to a poor prognosis, no specific guidelines exist for diagnosing and treating these rare cases. The newborn’s condition improved following…

Cabergoline, which is often used as an off-label therapy for recurrent or persistent Cushing’s disease, is not associated with a high risk for impulse control disorders(ICDs), a concern raised about this kind of medication. These are the findings of a small study in Turkey that suggests cabergoline “still holds…

A 52-year-old man developed Cushing’s syndrome after taking Artri King, adding to the list of reports that link the supplement to developing the condition. The man had been taking Artri King for his arthritis for 1.5 years, but abruptly stopped after having Cushing’s-like symptoms. His abrupt cessation is…

A 40-year-old woman developed exogenous, or therapy-related, Cushing’s syndrome, after taking an over-the-counter supplement called Artri King that contained undisclosed glucocorticoids, a case study reports. The woman’s symptoms eased after she stopped taking the supplement, but this is the third study to report an association between products like Artri King…

A 17-year old girl with Cushing’s syndrome developed atypical features of depression that were accompanied by suicide attempts and acute psychosis, both rarely reported in these patients. According to the case study’s authors, people with Cushing’s syndrome often experience depression, but this can have a wide range of manifestations…

A rare case of Cushing’s syndrome in a 3-month-old girl was traced to a medication error involving glucocorticoid, with the infant having been given an oral liquid formulation of omeprazole, prepared by a local pharmacist, that contained small amounts of the steroid hormone. The baby was being treated with omeprazole —…

Enrollment is nearly complete for a Phase 3 trial that is investigating the safety and effectiveness of relacorilant in people with Cushing’s syndrome due to any underlying cause, according to a corporate update from its developer, Corcept Therapeutics. The trial, called GRACE (NCT03697109), is enrolling about 130 people…

The prevalence of infection by SARS-CoV-2, the virus that causes COVID-19, was found to be similar in people with Cushing’s disease to that of the general population, according to an Italian study. The same was seen for patients in Southern Italy with acromegaly, a disorder marked by the…