People with Cushing’s syndrome have significant changes in the levels of adipokines — cell signaling molecules produced by fatty tissue — a recent study reports. Such changes were also found to be associated with urine cortisol levels and blood adrenocorticotropic hormone (ACTH) levels, as well as several metabolic parameters.
A rare tumor in the prostate gland triggered Cushing’s syndrome in a man, a case study from Lebanon reports. The report, “ACTH-secreting metastatic prostate cancer with neuroendocrine differentiation,” was published in BMJ Case Reports. Cushing’s syndrome is caused by an excess of cortisol in the body. It sometimes…
People with pituitary gland tumors that cause Cushing’s disease are at higher risk of developing ocular hypertension — increased blood pressure inside the eyes — than those with other types of pituitary tumors, according to a study in China. Its authors highlighted the importance of these results in ensuring ophthalmologists…
Young children may be at high risk of developing Cushing’s syndrome after having a highly potent topical glucocorticoid applied to the skin, two case reports show. The researchers emphasized that physicians who prescribe these medications must be aware for this potential side effect and closely monitor patients. They also…
A rare plurihormonal tumor in the brain’s pituitary gland — one that produced and released both adrenocorticotrophic hormone (ACTH) and growth hormone — caused Cushing’s disease in a woman in her 30s, a case study reported. Given the rarity of tumors in which both types of hormones are produced,…
Treatment with Isturisa (osilodrostat) caused adrenal insufficiency — a condition in which the adrenal glands are unable to produce enough of certain hormones — in a 41-year-old woman with Cushing’s disease, a case report showed. While the researchers noted that “monitoring for side effects and biochemical and clinical…
Adrenal gland removal was key to controlling high cortisol levels and improving the quality of life of a 33-year-old male patient with Cushing’s disease and recurrent bone fractures. Researchers stressed that “when osteoporotic fractures occur at a young age, it is important to exclude secondary causes, such as Cushing’s…
Horizon Therapeutics has launched its #RAREis Representation program aimed at increasing diversity, equity, and inclusion among patients with rare diseases. There are about 400 million people worldwide living with a rare disease; for many of them, access to diagnosis, care, and treatments can be challenging. Accessing better care depends on…
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