Keytruda Found Ineffective in Rare Case of Adrenal Cancer Caused by Lynch Syndrome, Report Shows
Keytruda (pembrolizumab) may not be effective in Lynch syndrome patients — those with inherited mutations in certain DNA repair genes — who develop Cushing’s syndrome due to cortisol-secreting metastatic adrenal cancer, a case report suggests. The report, “Rapid disease progression in a patient with mismatch…