GNAS Mutations May Help Identify Mechanisms of Subclinical Cushing’s, Report Suggests

Mutations in the GNAS gene might indicate patients with subclinical Cushing’s syndrome — mild cortisol elevation without physical signs of Cushing’s — whose disease is caused by distinct mechanisms of other Cushing’s syndrome patients. Screening for GNAS gene mutations may help diagnose patients with this type of Cushing’s syndrome and improve their outcomes,…