Fluconazole – a treatment for fungal infections – effectively reduced cortisol levels in people with Cushing’s syndrome, without causing significant liver damage, a study in Taiwan showed. According to researchers, these results suggest that fluconazole “may be an effective and safe option for managing” high cortisol levels in people…
The case of a 70-year-old U.S. man with ectopic Cushing’s syndrome caused by an unusual type of nasal tumor, called an olfactory neuroblastoma, was described in a report that, according to its author, “demonstrates the necessity of collaboration among endocrinology, otolaryngology, neurosurgery, radiology, and oncology teams in managing rare ACTH-secreting…
A 21-year-old woman in Iran developed Cushing’s syndrome after using a nasal corticosteroid for about a year, according to a recent case study. The report highlights a warning for patients and doctors: even non-oral steroids, like those delivered through the nose, can lead to serious side effects with prolonged use.
A pituitary tumor and thyroid cancer were found in a 43-year-old woman with cyclic Cushing’s syndrome, a form of Cushing’s in which cortisol levels rise and fall over time, according to a case report from China. The researchers noted that such fluctuations in a person’s cortisol levels can throw off…
A rare type of nasal tumor called olfactory neuroblastoma caused ectopic Cushing’s syndrome in a 56-year-old woman, according to a recent case report. The condition was effectively managed with the cortisol-lowering medication metyrapone before being followed by surgery and radiotherapy. After starting metyrapone, the woman developed an opportunistic lung infection,…
People with adrenal Cushing’s syndrome who were diagnosed in the 2000s often had the condition identified incidentally — but also experience fewer symptoms specific to Cushing’s compared with individuals receiving a diagnosis in previous decades, a study in Japan has found. However, the prevalence of Cushing’s-related complications, including cardiovascular events…
An adrenocorticotropic hormone (ACTH)-producing pheochromocytoma, a rare type of tumor in the adrenal gland, was the cause of Cushing’s syndrome in a 42-year-old woman, according to a case report in Mexico. The woman had no typical signs of Cushing’s, which delayed her diagnosis and made her “case particularly difficult…
Despite the known risk of osteoporosis among people with Cushing’s syndrome, only about 6% underwent bone mineral density (BMD) analysis within two years of diagnosis, a study using an insurance database shows. BMD testing assesses levels of calcium and other minerals in bone. Osteoporosis, which is characterized by…
A woman in her early 30s who developed severe ectopic Cushing’s syndrome due to a small thymus tumor was effectively managed with medications to reduce cortisol levels followed by surgery, according to a case report from Poland. After the initial surgery, the patient experienced two recurrences of Cushing’s within seven…
A woman in Switzerland with metastatic lung cancer who developed thin skin and was later diagnosed with Cushing’s syndrome was the subject of a repoort by researchers. Metastatic cancer occurs when the disease has spread from its original site to other parts of the body. In this case, Cushing’s was…
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