Iqra Mumal, MSc,  —

The Cushing’s syndrome therapy mifepristone can alleviate a liver condition that often develops along with Cushing’s, a case study suggests. The disorder, which involves too many fat deposits in the liver, is called non-alcoholic fatty liver disease, or NAFLD. Researchers examined the case of a 49-year-old woman with Cushing’s syndrome and NAFLD…

In Europe, nearly 20 percent of patients with Cushing’s syndrome receive some sort of medication for the disease before undergoing surgery, a new study shows. Six months after surgery, these patients had remission and mortality rates similar to those who received surgery as a first-line treatment, despite having worse disease…

Therapies known as histone deacetylase inhibitors reduced fatty liver disease in a rat model of Cushing’s syndrome, a study reports. (HDACi) was found to reduce hepatic steatosis – also known as fatty liver disease – in a rat model of Cushing’s syndrome, according to a new study. Researchers’ article, “Histone…

Lower muscle mass and higher visceral fat are correlated to higher cortisol levels, and can be used as reliable biomarkers to assess disease severity in patients with adrenal adenomas, a new study shows. The study, “Impact of hypercortisolism on skeletal muscle mass and adipose tissue mass in…

Hydrocortisone and prednisone have comparable safety and effectiveness when used as glucocorticoid replacement therapy in patients with adrenal adenoma or Cushing’s disease who underwent adrenalectomy, a new study shows. The study, “Comparison of hydrocortisone and prednisone in the glucocorticoid replacement therapy post-adrenalectomy of Cushing’s Syndrome,” was published in the journal…

Patients with different subtypes of Cushing’s syndrome (CS) have distinct plasma steroid profiles. This could be used as a test for diagnosis and classification, a German study says. The study, “Plasma Steroid Metabolome for Diagnosis and Subtyping Patients with Cushing Syndrome,” appeared in the journal Clinical Chemistry. A…

Pregnant woman with hypertension and significant signs of hypercortisolism (high cortisol levels) may have Cushing’s disease, according to a new case report. The report, titled “A Case of Cushing’s Syndrome in Pregnancy,” was published in the Iranian Journal of Medical Sciences. While Cushing’s rarely occurs…

All patients who undergo removal of one adrenal gland due to Cushing’s syndrome (CS) or adrenal incidentaloma (AI, adrenal tumors discovered incidentally) should receive a steroid substitutive therapy, a new study shows. The study, “Predictability of hypoadrenalism occurrence and duration after adrenalectomy for ACTH‐independent hypercortisolism,” was published…

Premenopausal women whose Cushing’s syndrome is in remission are at high risk of having a heart problem even if they don’t have a cardiovascular disease, a study shows. The research, “Translational evidence of prothrombotic and inflammatory endothelial damage in Cushing Syndrome after remission,” was published in the…

Certain regions of the brain in patients with Cushing’s disease are associated with altered metabolism, indicating a mechanism of cognitive impairment, new study shows. The study, “Voxel-based comparison of brain glucose metabolism between patients with Cushing’s disease and healthy subjects,” was published in the journal…