Author Archives: Jose Marques Lopes PhD

Certain Comorbidities of Cushing’s Syndrome May Lead to More Complications After Remission, Study Finds

A patient’s age, urinary-free cortisol (UFC) level, fasting glucose — a measure of insulin resistance — body mass index (BMI), and the number of comorbidities at diagnosis for Cushing’s syndrome predicted the number of long-term comorbidities several years after remission, according to a study. Specifically, older age, lower baseline UFC,…

Less Visceral Obesity and Better Muscle Mass Seen in Patients After Adrenal Gland Removal, Study Says

Patients with Cushing’s syndrome showed less abdominal fat and increased muscle mass, as well as reduced use of medications one year after having their adrenal glands removed, according to a new study. The research, “Changes of computed tomography-based body composition after adrenalectomy in patients with endogenous hypercortisolism,” was…

Metopirone Normalizes Cortisol Levels, Improves Clinical Parameters in Cushing’s Patients When Used Pre-Surgery, Study Finds

Pre-surgery treatment of adrenocorticotropic hormone (ACTH)-independent Cushing’s syndrome with Metopirone (metyrapone) leads to effective and safe improvement of hormonal levels and clinical parameters, according to a new pilot study. The research, “Preoperative treatment with metyrapone in patients with Cushing’s syndrome due to adrenal adenoma: a pilot prospective…