Author Archives: Jose Marques Lopes PhD

Temozolomide May Partially Improve Aggressive Pituitary Tumors Causing Cushing’s Disease, Case Study Suggests

The chemotherapy temozolomide partially improved a case of an aggressive pituitary tumor that caused symptoms of Cushing’s disease (CD), according to a new study in Poland. However, after tumor mass and cortisol levels were stabilized for a few months, the patient experienced rapid progression, suggesting that new methods for extending the…

Laparoscopic Adrenalectomy Is Safe and Effective to Remove Larger Adrenal Tumors, Study Reports

The minimally invasive laparoscopic adrenalectomy (LA) is a safe and feasible procedure for larger adrenal tumors and metastasis, a new Italian study shows. While the findings suggest that the surgical application of laparoscopic adrenalectomy could be extended, surgeons should undergo a 30-procedure learning curve to improve surgical outcomes, researchers say.

Increase in Glucose Uptake by Cushing’s Disease-associated Tumors Could Improve Early Detection, Study Shows

An increase in glucose uptake by Cushing’s disease-associated pituitary tumors could improve their detection, new research shows. The study, “Corticotropin releasing hormone can selectively stimulate glucose uptake in corticotropinoma via glucose transporter 1,” appeared in the journal Molecular and Cellular Endocrinology. The study’s senior author was Dr.