Margarida Maia, PhD,  science writer—

Measuring cortisol in a small sample of saliva collected late at night may work just as well as the 24-hour urine test — which involves collecting urine passed during the day and night — for checking whether Cushing’s disease is in remission after radiotherapy, a study by U.S. researchers…

Surgery for Cushing’s disease eases symptoms and improves heart health more effectively than medication, a new study by researchers at the University Hospital of Padova in Italy has found. However, some problems — specifically including obesity and high blood pressure — can still remain, especially if cortisol is not…

Endoscopic transsphenoidal surgery, which allows a surgeon to gain access to the brain through the nose to remove a pituitary tumor causing Cushing’s disease, was found to be safe and effective for bringing about remission in children, with few complications. While this surgery is usually done in adults with…

One person out of five with Cushing’s syndrome in Israel has higher than normal numbers of white blood cells that drop within two years after surgery, but may still remain higher than the general population, a study finds.  Patients with Cushing’s disease, a specific type of Cushing’s syndrome…

People with Cushing’s syndrome, including those with Cushing’s disease, are at a higher risk of developing cataracts, causing blurry vision, than the general population, a study from Israel finds. Cataracts, which occur when the eye’s lens becomes cloudy, also developed nearly three years earlier than in the general population,…

Patients being treated with Isturisa (osilodrostat) for Cushing’s disease see better long-term clinical outcomes when both late-night salivary cortisol and mean urinary free cortisol returned to normal levels, instead of just one or neither of those measures. Drawing on data from two Phase 3 clinical studies, LINC-3…

All patients who completed a Phase 2 clinical trial of clofutriben, an oral small molecule that Sparrow Pharmaceuticals is developing for endogenous Cushing’s syndrome, chose to continue on the experimental treatment as part of a planned open-label extension. Overall, the results of the trial, dubbed RESCUE, showed promise, Sparrow…

Yana Zavros, PhD, a physiologist working on Cushing’s disease, has been named the Georgia Research Alliance’s eminent scholar in molecular medicine. She will establish and direct a new research center at the University of Georgia’s School of Medicine, focusing on translating laboratory observations into clinical practice. The center will…

Cushing’s disease appears to be on the rise in Iceland, a study finds, underscoring the importance of an early diagnosis. “Advances in diagnostic and treatment options is probably the strongest cause of increased incidence in the later years, but other factors such as genetics can also play a role,”…

A 76-year-old man in Greece developed ectopic Cushing’s syndrome due to an advanced prostate cancer that started producing the adrenocorticotropic hormone (ACTH), leading to unusual symptoms such as muscle weakness, slowed thinking, and low potassium levels. Despite immediate treatment, his clinical condition worsened, and he eventually died. It’s a…