Margarida Maia, PhD,  science writer—

Cushing’s disease caused a bowel perforation — a rare complication in which a hole in the intestine allows its contents to leak — requiring a young man in Japan to undergo emergency surgery. His case was described in the report “Bowel perforation associated with Cushing’s disease: a case…

A young man developed an asymptomatic form of Cushing’s syndrome — called subclinical Cushing’s syndrome — as a result of a pheochromocytoma, a tumor that can form in the adrenal glands and is usually benign, according to a report from Nepal. “Diagnosing these conditions can be challenging as they…

For a young man in Brazil, Cushing’s syndrome caused by nodules in both adrenal glands was found to be the reason for his severe osteoporosis — a condition that causes bones to weaken and become prone to fracture — according to a case report. While noting that “the diagnosis of…

People with Cushing’s disease who have been in remission for years may have an imbalance in their gut microbiome — the group of all microorganisms living in the gut — and this may be the reason why their cardiovascular risk persists, a pilot study suggests. The small study included…

An antifungal medication called ketoconazole may be safe and effective for treating Cushing’s disease when pituitary surgery to remove a disease-causing tumor has failed to lower cortisol levels in the body, according to a new meta-analysis study. Researchers found that in nearly two-thirds of cases reported in the literature,…

A high-resolution MRI outperformed other types of MRI at detecting microadenomas — small benign (noncancerous) tumors that form in the brain’s pituitary gland and can cause Cushing’s disease. In a small study from China, about four in five people with Cushing’s received a correct diagnosis of a microadenoma with…

A woman developed Cushing’s syndrome as a result of a pheochromocytoma, a usually benign non-cancerous tumor that forms in the adrenal glands above the kidneys, a case study from Portugal reports. Because it’s so rare, “this diagnosis demands a high level of clinical suspicion and should be equated in the…

A young woman developed Cushing’s disease after she received pain relief treatment for her chronic pancreatitis — a long-lasting inflammation of the pancreas — via a celiac plexus block (CPB) with a corticosteroid called triamcinolone, a U.S. report says. “Although her pain was relieved with CPB, she developed iatrogenic…

A woman who was on Korlym (mifepristone) to treat hyperglycemia, or high blood sugar levels, linked to Cushing’s disease went on to develop liver damage as a side effect of the medicine, according to a U.S. report. This is the third time such a case has been reported.

A woman developed Cushing’s syndrome five years after being diagnosed with a neuroendocrine tumor of the cervix, according to a report from the U.S. This is a rare type of tumor for which “the options for treatment are few and not necessarily curative,” the report’s authors wrote. “Managing the…