Marisa Wexler, MS,  senior science writer—

A woman with undiagnosed Cushing’s disease experienced a resolution of her hypercortisolism symptoms after a spontaneous pituitary apoplexy, and was retrospectively diagnosed via hair cortisol analysis, according to a recent case report. This study highlights the utility of testing cortisol levels in hair as a means of identifying…

People with Cushing’s syndrome experience muscle weakness that persists even when the disorder is in remission, a new study shows. The study, “Persisting muscle dysfunction in Cushing’s syndrome despite biochemical remission,” was published in The Journal of Clinical Endocrinology and Metabolism. Cushing’s syndrome is characterized by…

People with Cushing’s syndrome commonly experience cognitive and emotional problems, a new study indicates. The study, “Neuropsychological and Emotional Functioning in Patients with Cushing’s Syndrome,” was published in Behavioural Neurology. Cushing’s syndrome is characterized by abnormally high levels of the hormone cortisol. (Cushing’s disease…

Treatment with Isturisa (osilodrostat) led to a rapid and sustained reduction in cortisol levels and was well-tolerated in people with Cushing’s disease, according to newly published data from the LINC-3 clinical trial. The results were published in The Lancet Diabetes & Endocrinology, in the article “…

Isturisa (osilodrostat) is now available in Germany to treat adults with endogenous Cushing’s syndrome. The announcement by Recordati Rare Diseases, which acquired rights to Isturisa from its original developer Novartis, follows the medication recently becoming available in the U.S. and in France. Isturisa…

A newly developed smart contact lens might be used to measure levels of the hormone cortisol in a person’s tears, which could be helpful in disorders such as Cushing’s disease. The new device was described in Science Advances, in the study, “Smart, soft contact lens for…

Cushing’s syndrome treatment Isturisa (osilodrostat) now is commercially available in France. The announcement from Recordati Rare Diseases comes soon after the medication became fully available for sale and distribution to adults in the U.S. The company stated that the medication will be made available elsewhere in the European Union…

Making incisions through the back of the body, rather than the front, can lessen bleeding and shorten operation time during surgery to remove the adrenal glands, a new study suggests. The study, “Comparison of synchronous bilateral transperitoneal and posterior retroperitoneal laparoscopic adrenalectomy: results of a multicenter study,”…

Cushing’s syndrome can occur during pregnancy without obvious signs and symptoms specific to the condition, a new case report shows, suggesting the disease should be considered as a diagnosis in cases of high blood pressure during early pregnancy. The case report, “A case of subclinical Cushing’s…

Undiagnosed tumors on the adrenal glands — called adrenal incidentalomas, because they are found by chance — may be more prevalent than previously thought and also may be linked to an increased risk of type 2 diabetes, a new study has found. The study, “Adrenal incidentalomas…