Marisa Wexler, MS,  senior science writer—

Nearly one out of four people with difficult-to-treat type 2 diabetes also has Cushing’s syndrome, according to preliminary data from the Phase 4 CATALYST clinical trial. “These results are very powerful,” Ralph DeFronzo, MD, an investigator on the CATALYST study and professor of medicine at UT Health San Antonio,…

Singapore’s Health Sciences Authority (HSA) has issued a warning that Gu Jie Ling, an herbal concoction marketed as a “traditional medicine,” contains a drug called dexamethasone that can cause Cushing’s syndrome, and has advised the public not to purchase or consume it. The HSA recommends that people who have…

Two unusual cases of Cushing’s syndrome caused by pancreatic tumors that had spread to the liver were described in a recent report, highlighting the importance of assessing the presence of Cushing’s in people with pancreatic tumors who continue to show signs of the disorder. The disorder, called ectopic ACTH syndrome…

The unusual case of a woman with Cushing’s syndrome caused by an adrenal tumor who experienced recurring episodes of blood clots in the lungs was described in a recent report. The study, “Adrenocorticotropic hormone-secreting phaeochromocytoma as a cause of treatment-resistant hypertension and recurrent pulmonary emboli,” was published…

A five-week, low-calorie ketogenic diet led to weight loss and reduced blood pressure in people with Cushing’s disease in a small study. The diet also lowered blood levels of cholesterol and other fatty molecules, but did not alter cortisol levels, which are typically elevated in Cushing’s patients. Findings were…

Corcept Therapeutics is expecting to earn nearly $500 million in revenue this year, which is due in large part to the increased recognition of Cushing’s syndrome, the company noted in a recent corporate update. Corcept, which markets Korlym (mifepristone) — a therapy approved to control high blood sugar in…

People with Cushing’s disease have differences in brain activity that significantly associate with the severity of cognitive and mental health symptoms, implying such changes in brain activity may give rise to these symptoms. That’s according to the recent study “Dynamic functional connectivity changes associated with psychiatric traits and…

Cushing’s disease caused by Crooke cell adenoma — a rare but typically more aggressive pituitary tumor — is less likely than forms of the disease associated with other types of pituitary tumors to go into remission in the months following surgery. This is true despite the fact that surgery…

A woman developed Cushing syndrome after four months of taking supplements that contained a steroid, which she was not aware of because the supplement did not mention it on its label, according to a case report. “This case highlights the importance of educating patients to exercise caution when purchasing health…

Despite repeatedly testing negative for high cortisol levels on standard lab tests, a woman in her 30s was found to have Cushing’s syndrome after undergoing a specialized blood analysis. That test allowed doctors to measure the levels of the hormone cortisol — too much of which is a hallmark of…