Marisa Wexler, MS,  senior science writer—

Cushing’s Awareness Day is April 8, and the Cushing’s community is gearing up with events and fundraising efforts to spread awareness and raise money to combat the disorder. In celebration of this year’s Awareness Day, Xeris Pharmaceuticals, which markets Cushing’s treatment Recorlev (levoketoconazole), is teaming up with the…

A Phase 3 trial testing the oral medication relacorilant in people with Cushing’s syndrome caused by adrenal adenoma, a type of adrenal gland tumor, or adrenal hyperplasia, a condition in which the adrenal glands become enlarged, has finished enrolling participants. Relacorilant’s developer, Corcept Therapeutics, said 137 participants have…

An interaction between an anti-inflammatory steroid and an anti-fungal medication led to the onset of Cushing’s syndrome and reduced adrenal gland function in a man being treated for complications from a bone marrow transplant. A case report on the 67-year-old man’s symptoms highlights possibly serious consequences from these medicines’…

A rare adrenal tumor turned out to be the cause of a man’s Cushing’s syndrome, according to a case report from China. The man had severe metabolic complications related to Cushing’s, but these resolved rapidly following surgical removal of the disease-driving tumor, called a pheochromocytoma. Diagnosing and managing a pheochromocytoma…

Nearly one out of four people with difficult-to-treat type 2 diabetes also has Cushing’s syndrome, according to preliminary data from the Phase 4 CATALYST clinical trial. “These results are very powerful,” Ralph DeFronzo, MD, an investigator on the CATALYST study and professor of medicine at UT Health San Antonio,…

Singapore’s Health Sciences Authority (HSA) has issued a warning that Gu Jie Ling, an herbal concoction marketed as a “traditional medicine,” contains a drug called dexamethasone that can cause Cushing’s syndrome, and has advised the public not to purchase or consume it. The HSA recommends that people who have…

Two unusual cases of Cushing’s syndrome caused by pancreatic tumors that had spread to the liver were described in a recent report, highlighting the importance of assessing the presence of Cushing’s in people with pancreatic tumors who continue to show signs of the disorder. The disorder, called ectopic ACTH syndrome…

The unusual case of a woman with Cushing’s syndrome caused by an adrenal tumor who experienced recurring episodes of blood clots in the lungs was described in a recent report. The study, “Adrenocorticotropic hormone-secreting phaeochromocytoma as a cause of treatment-resistant hypertension and recurrent pulmonary emboli,” was published…

A five-week, low-calorie ketogenic diet led to weight loss and reduced blood pressure in people with Cushing’s disease in a small study. The diet also lowered blood levels of cholesterol and other fatty molecules, but did not alter cortisol levels, which are typically elevated in Cushing’s patients. Findings were…

Corcept Therapeutics is expecting to earn nearly $500 million in revenue this year, which is due in large part to the increased recognition of Cushing’s syndrome, the company noted in a recent corporate update. Corcept, which markets Korlym (mifepristone) — a therapy approved to control high blood sugar in…