Cushing’s Linked to Structural, Functional Changes in Brain’s Hippocampus

People with Cushing’s disease have structural and functional changes in the hippocampus — a brain region involved in memory, emotions, and stress responses — relative to healthy individuals, a small study shows. All four hippocampus subregions were smaller in Cushing’s patients and the connectivity to brain networks involved in…

Brain Tissue Changes in Cushing’s Syndrome May Correlate with Disease Symptoms, Study Suggests

In addition to changes in volume of certain brain structures, people with Cushing’s syndrome also show widespread changes in the consistency of brain tissue, namely in white matter, which is made of nerve fibers or axons.  Importantly, such changes may correlate with disease symptoms. The study with those findings,…