Andrea Lobo,  —

A 44-year-old woman was found to have a hormone-producing tumor in her left adrenal gland, which produced and released both cortisol and testosterone, leading to the onset of Cushing’s syndrome. The high levels of testosterone produced and released by the tumor also caused her to develop virilization, a condition in…

About five months of treatment with relacorilant significantly reduced both high blood pressure and high blood sugar levels in people with endogenous Cushing’s syndrome, according to data from a Phase 3 trial. Relacorilant also was found to be generally safe and well tolerated, and to be able to significantly…

A 66-year-old woman in South America was diagnosed with Cushing’s disease after being referred for a consultation with a specialist for obesity associated with pain and reduced mobility in the right knee, according to a new case study. Titled “From Knee Pain Consultation to Pituitary Surgery: The Challenge…

Changes in blood flow linked to obesity start in the early stages of Cushing’s disease, as evidenced by a significant decrease in the blood-pumping ability of the heart, a new study reported. While obese patients appeared to have normal heart function in standard echocardiographic examinations, a noninvasive method called…

A rare type of nasal tumor, called olfactory neuroblastoma, caused ectopic Cushing’s syndrome in a 47-year-old man, as described in a recent case report. Surgical treatment led to a reduction of the patient’s blood cortisol and adrenocorticotropic hormone (ACTH) levels, which were elevated as a result of the tumor. “This…

A timely diagnosis of Cushing’s syndrome during pregnancy, along with appropriate individualized treatment, is critical for minimizing complications for the mother and the child, according to a case series study that followed five pregnant women with Cushing’s caused by adrenal tumors at a hospital in China. “By implementing a multidisciplinary…

A 40-year-old man who developed ectopic Cushing’s syndrome as a result of a lung tumor remained undiagnosed for years, despite showing Cushing’s symptoms and progressive physical and mental decline, a recent case study shows. Once he was diagnosed, surgery to remove the tumor resulted in his health improving substantially.

Individuals with Cushing’s syndrome have a greater buildup of fat around the heart and inside the coronary arteries — the blood vessels that supply blood to the heart — compared with people who don’t have the condition but who are at a higher risk of developing cardiovascular disease, according to…

The rare case of Cushing’s syndrome due to a cortisol-producing adrenal tumor and acromegaly that resulted from a growth-hormone-producing tumor in the pituitary gland was described in a recent report. Acromegaly occurs when the pituitary gland produces excessive amounts of growth hormone during adulthood, resulting in…

Isturisa (osilodrostat) was able to successfully treat ectopic Cushing’s syndrome due to a lung tumor in a 68-year-old man with lung cancer, according to a recent case report. Treatment led to a reduction in the patient’s blood cortisol levels, which were elevated as a result of the lung tumor…