News

A severe muscle infection and electrolyte imbalances were among clinical signs leading to a Cushing’s syndrome diagnosis in an 82-year-old woman, according to a recent case report. The patient also showed other cardiovascular risk factors for Cushing’s that aided clinicians in their diagnosis. Infectious complications after a surgery caused the…

A 49-year-old woman developed exogenous, or therapy-related, Cushing’s syndrome, after being treated with the antiviral Epclusa, which is approved to treat hepatitis C virus infections, a case study reported. “To our knowledge, this is the first time that [Epclusa] has been linked to [exogenous Cushing’s],” the researchers wrote. The study,…

People with Cushing’s syndrome have significant changes in the levels of adipokines — cell signaling molecules produced by fatty tissue — a recent study reports. Such changes were also found to be associated with urine cortisol levels and blood adrenocorticotropic hormone (ACTH) levels, as well as several metabolic parameters.

In rare cases, proximal muscle weakness may be the only indication of Cushing’s disease, a recent case report showed. The patient, a 36-year-old man, was initially misdiagnosed with dermatomyositis, a rare disease that causes muscle inflammation and skin rash. The report, “Proximal muscle weakness as the sole manifestation…

A rare tumor in the prostate gland triggered Cushing’s syndrome in a man, a case study from Lebanon reports. The report, “ACTH-secreting metastatic prostate cancer with neuroendocrine differentiation,” was published in BMJ Case Reports. Cushing’s syndrome is caused by an excess of cortisol in the body. It sometimes…

Throughout 2022, Cushing’s Disease News has brought you coverage of the latest developments in research and advances in treatment related to Cushing’s disease. We look forward to continuing to serve as a resource for the Cushing’s community going into 2023. Here is a list of the top 10…

People with pituitary gland tumors that cause Cushing’s disease are at higher risk of developing ocular hypertension — increased blood pressure inside the eyes — than those with other types of pituitary tumors, according to a study in China. Its authors highlighted the importance of these results in ensuring ophthalmologists…

Young children may be at high risk of developing Cushing’s syndrome after having a highly potent topical glucocorticoid applied to the skin, two case reports show. The researchers emphasized that physicians who prescribe these medications must be aware for this potential side effect and closely monitor patients. They also…

Adults and children with endogenous Cushing’s syndrome in Colombia will have access to Metopirone (metyrapone), the first Cushing’s treatment to be approved in the country, HRA Pharma Rare Diseases, which developed and markets the treatment, announced. With this registration, Colombia joins several other countries, including in Europe, the…

The hormone aldosterone may contribute to high blood pressure in people with subclinical hypercortisolism — those who have high levels of cortisol due to tumors in the adrenal glands, but do not have overt symptoms of Cushing’s syndrome. Aldosterone, excessively produced and released by the adrenal glands in these patients,…