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Young people with Cushing’s disease who have low bone density also tend to have low levels of insulin-like growth factor 1 (IGF-1), a signaling molecule that’s known to play key roles in bone development, a new study shows. “Our study found that a higher IGF-1 index was independently and significantly…

A woman who developed Cushing’s syndrome as a complication of kidney cancer saw her symptoms fully resolve after the tumor was surgically removed. This is the first published account that definitively describes Cushing’s syndrome developing as a paraneoplastic (cancer-related) complication of this type of cancer and resolving after its removal,…

A 37-year-old woman diagnosed with Cushing’s disease following childbirth experienced a pulmonary embolism — a blockage in blood flow to the lungs that’s generally caused by blood clots — as one of the first symptoms of the rare disorder. According to clinicians, her case highlights that pulmonary embolism may…

A 40-year-old woman developed exogenous, or therapy-related, Cushing’s syndrome, after taking an over-the-counter supplement called Artri King that contained undisclosed glucocorticoids, a case study reports. The woman’s symptoms eased after she stopped taking the supplement, but this is the third study to report an association between products like Artri King…

Cushing’s disease caused a bowel perforation — a rare complication in which a hole in the intestine allows its contents to leak — requiring a young man in Japan to undergo emergency surgery. His case was described in the report “Bowel perforation associated with Cushing’s disease: a case…

A 17-year old girl with Cushing’s syndrome developed atypical features of depression that were accompanied by suicide attempts and acute psychosis, both rarely reported in these patients. According to the case study’s authors, people with Cushing’s syndrome often experience depression, but this can have a wide range of manifestations…

A woman developed Cushing’s syndrome as a result of a rare pituitary tumor in the clivus region — a bone at the base of the skull — that produced excess levels of the adrenocorticotropic hormone (ACTH), a case study from China reports. This is a very rare case of…

A young man developed an asymptomatic form of Cushing’s syndrome — called subclinical Cushing’s syndrome — as a result of a pheochromocytoma, a tumor that can form in the adrenal glands and is usually benign, according to a report from Nepal. “Diagnosing these conditions can be challenging as they…

For a young man in Brazil, Cushing’s syndrome caused by nodules in both adrenal glands was found to be the reason for his severe osteoporosis — a condition that causes bones to weaken and become prone to fracture — according to a case report. While noting that “the diagnosis of…

An imaging abnormality that makes it harder for clinicians to visualize the brain’s pituitary gland can complicate efforts to diagnose and manage Cushing’s disease, a recent report highlights. The abnormality affects the bony compartment that houses the pituitary gland, making “visual diagnosis of pituitary adenoma [benign tumors] even more…