The U.S. Food and Drug Administration (FDA) is reviewing an application from Strongbridge Biopharma seeking the approval of Recorlev (levoketoconazole) for the treatment of endogenous Cushing’s syndrome. A final decision from the FDA is expected by Jan. 1, 2022 — meaning that Recorlev’s approval request will follow the…
News
The case of an elderly woman who developed shingles triggered by subclinical Cushing’s disease, and later died from sudden cardiac arrest, underscores the importance of closely monitoring immune responses in patients showing signs of that disorder. Her case was described in the…
Chronic insomnia can be a sign of Cushing’s syndrome, and doctors need be aware of this possibility, according to a case report of a woman diagnosed with Cushing’s shortly after seeking help for her insomnia. This case also emphasized the usefulness of the dexamethasone suppression test in identifying the specific…
A woman with a rare case of Cushing’s disease, in which rising cortisol triggered the production of yet more cortisol, may represent a new subtype of the disorder. She was the focus of the recent case report “Tumor shrinkage by metyrapone in Cushing’s disease exhibiting glucocorticoid-induced…
Screening for endocrine disorders, such as Cushing’s syndrome, is particularly important in patients who have tumors in hormone-producing endocrine glands, such as the thyroid. This was the take-home message of a recent case report study that described the case of a woman with thyroid cancer who also had Cushing’s driven…
Cushing’s syndrome may increase the risk of acute pancreatitis, a condition in which the pancreas becomes inflamed suddenly, according to a recent case report. The study, “Acute pancreatitis associated with Cushing syndrome – A case report and literature review…
More than half of the people with rare diseases and their caregivers, asked in a survey, were undecided or less than willing to be vaccinated for COVID-19 if a vaccine was approved under emergency use authorization instead of the routine process, the EveryLife Foundation for Rare Disease reports. These findings…
Clinical outcomes of COVID-19 in people with Cushing’s syndrome seem to depend on the severity of hypercortisolism, or how high blood cortisol levels are in these patients, according to a recent case series study. “Severe hypercortisolism is a warning sign that [Cushing’s syndrome] affected by COVID-19…
The EveryLife Foundation for Rare Diseases is accepting applications for a scholarship program that aims to help adults with a rare disease pursue personal goals through training and education. For a second year, the #RAREis Scholarship Fund — supported by Horizon Therapeutics – will award 35 one-time scholarships, each…
Cortisol fluctuations in a woman with Cushing’s disease were controlled successfully with Signifor (pasireotide LAR), possibly for the first time, according to a recent case report. The report, “Resolution of cyclicity after pasireotide LAR in a patient with Cushing’s disease,” was published in the journal…
Recent Posts
- Unexpected insulin resistance exposes rare Cushing’s disease diagnosis
- The challenges of managing Cushing’s disease during the postpartum period
- Test may be ‘practical’ alternative for diagnosing Cushing’s in kids
- Man’s aggressive salivary gland cancer triggers Cushing’s syndrome: Report
- FDA rejects relacorilant for Cushing’s-related high blood pressure
- Study supports Isturisa as first-line ectopic Cushing’s treatment
- After some scary complications, I finally gave birth to a baby girl
- Rare dual diagnosis explains man’s chronic high blood pressure: Report
- Woman with recurrent Cushing’s disease has 2 successful pregnancies
- Real-world study backs Isturisa for non-pituitary Cushing’s forms