News

Patients with Cushing’s disease may develop post-traumatic stress symptoms, which are generally resolved once they undergo surgery to remove the tumor, but can persist in some cases, a study shows. The study, “Posttraumatic stress symptoms (PTSS) in patients with Cushing’s disease before and after surgery: A prospective…

Europe’s umbrella organization for 800 rare disease associations has developed a sweeping initiative to help the continent’s 30 million rare disease patients and their caregivers learn about their conditions, find assistance and receive treatment. Eurordis-Rare Diseases Europe hopes to improve the current piecemeal treatment and support program with a holistic,…

In the modern era, three new cases of Cushing’s syndrome are being diagnosed annually per one million inhabitants, according to results from a study conducted in a region of Sweden. Also, more patients with ectopic Cushing’s syndrome are being diagnosed compared to prior reports, which researchers attribute to an increased awareness…

People with rare diseases know that the right government policies can make a big difference in the quality of their own lives, and those of their caregivers. But most lawmakers aren’t experts in even one well-known disease — let alone the world’s estimated 7,000 rare disorders. So how does the…

The oral chemotherapy temozolomide might be an effective treatment for Cushing’s disease caused by aggressive tumors in the pituitary gland that continue to grow after surgery and taking other medications, a case report suggests. The study, “Successful reduction of ACTH secretion in a case of…

Clinical outcomes of Cushing’s disease patients who undergo endoscopic endonasal surgery to remove a pituitary adenoma are similar to those seen in patients who underwent previously used microscope-assisted techniques. According to a new study, that means despite the need for specialized training and equipment, using an endoscopic endonasal approach…

Giving corticotropin-releasing hormone (CRH) to Cushing’s disease patients helps improve the detection of pituitary tumors on positron emission tomography (PET) scans, increasing the chances of a more successful surgery, a study shows. The study, “CRH stimulation improves 18F-FDG-PET detection of pituitary adenomas in Cushing’s disease,” was published in the journal…

After receiving the approval of ketoconazole for the treatment of Cushing’s syndrome patients in the European Union, HRA Pharma is setting up to conduct a post-approval observation study that will closely monitor patients receiving the therapy for any adverse events. The study is part of the mandatory pharmacovigilance…

In some rare cases, Cushing’s disease patients have a benign pituitary tumor that produces several pituitary hormones in excess, rather than just the adrenocorticotropic hormone (ACTH). When these tumors also produce prolactin, they can be treated with dopamine agonists as an alternative to surgery, a case report suggests. The…

Removal of pituitary adenomas by inserting surgical instruments through the nose (transsphenoidal resection) remains the best treatment option for pediatric patients, despite its inherent technical difficulties, a new study shows. The study, “Transsphenoidal surgery for pituitary adenomas in pediatric patients: a multicentric retrospective study,” was…