Ketoconazole is a safe treatment for Cushing’s syndrome patients, but close monitoring of liver function markers should be done for up to six months, a French study shows. The study, “Hepatic safety of ketoconazole in Cushing’s syndrome: results of a compassionate use program in France,” appeared in the…
High lipid levels in the blood may lead to elevated blood pressure in patients with Cushing’s disease, a Chinese study shows. The study, “Evaluation of Lipid Profile and Its Relationship with Blood Pressure in Patients with Cushing’s Disease,” appeared in the journal Endocrine Connections. Patients with Cushing’s…
The Japan Endocrine Society (JES) has proposed new criteria, including reviewed cutoff values for blood cortisol levels, for the diagnosis of adrenal subclinical Cushing’s syndrome (SCS), a type of Cushing’s syndrome that lacks the clinical signs of the disease. The research, “New diagnostic criteria of adrenal subclinical Cushing’s…
Using magnetic resonance imaging (MRI) with superior magnetic strength enabled determination of precise tumor location in a patient with Cushing’s disease, a new case report describes. The research, “Value of pituitary gland MRI at 7 T in Cushing’s disease and relationship to inferior petrosal sinus sampling: case…
Assessment of late-night salivary cortisol (LNSC) levels is a poor diagnostic tool for detecting Cushing’s disease in obese patients, a new study from Germany shows. The test demonstrated a particularly poor sensitivity in obese people, meaning it will often suggest a patient has Cushing’s disease when that is not the case…
Detailed imaging analysis of patients with Cushing’s disease (CD) and other disorders caused by pituitary adenomas (tumors that arise from the pituitary, a small gland in the brain) provides correlation with clinical characteristics and treatment response, a new Turkish study reports. The research, “Clinicopathological…
The ratio between adrenocorticotropic hormone levels and cortisol levels in the blood is higher among Cushing’s disease patients than in healthy people, a new study has found, suggesting that measurement could be used to help diagnose the disease. Also, higher values at diagnosis could predict if the disease will recur…
Chronic alcoholism and associated magnesium and potassium deficiencies may cause a condition, called pseudo-Cushing’s syndrome, a recent case report from Japan shows. The research, “Hypokalemia associated with pseudo-Cushing’s syndrome and magnesium deficiency induced by chronic alcohol abuse,” was published in the journal CEN Case Reports. Chronic…
Non-cancerous adrenal gland tumors can lead to rare cases of Cushing’s syndrome in young children and puberty starting years before it should, a case study of a 5-year-old boy shows. Removing his right adrenal gland eliminated the problems, the Saudi Arabian researchers said. Their report dealt with tumors in epithelial cells,…
Measuring cortisol levels in saliva multiple times a day is a convenient and useful way to determine the best course of treatment for patients with Cushing’s syndrome, a preliminary study shows. The research, “Multiple Salivary Cortisol Measurements Are a Useful Tool to Optimize Metyrapone Treatment in Patients with…
Get regular updates to your inbox.