News

Corcept Therapeutics is expecting to earn nearly $500 million in revenue this year, which is due in large part to the increased recognition of Cushing’s syndrome, the company noted in a recent corporate update. Corcept, which markets Korlym (mifepristone) — a therapy approved to control high blood sugar in…

For a woman in her 60s in China, Cushing’s syndrome led to a myocardial infarction or heart attack, and to heart failure, according to a report on the rare case. The patient’s Cushing’s was secondary to an adrenocortical adenoma — a benign, or non-cancerous, tumor that formed in the…

More boys were diagnosed with Cushing’s disease before puberty than were girls, according to an examination of medical records of children and adolescent patients across Turkey. These findings contrast with observations made in adults, in whom women are diagnosed with Cushing’s far more often than men. The researchers noted,…

A 31-year-old woman exhibited unusual symptoms of Cushing’s disease following childbirth, but didn’t show some of the disease’s hallmark features, such as weight gain and fat accumulation. The woman’s atypical symptoms, which included psychosis and severe muscle weakness, were accompanied by a challenging clinical course that led ultimately…

For a man in Denmark, Cushing’s syndrome developed as a result of a medullary thyroid carcinoma — a tumor that formed in the thyroid gland in the neck and released corticotropin-releasing hormone (CRH), a hormone that triggers cortisol production. During the workup, however, results of inferior petrosal sinus sampling,…

People with Cushing’s disease have differences in brain activity that significantly associate with the severity of cognitive and mental health symptoms, implying such changes in brain activity may give rise to these symptoms. That’s according to the recent study “Dynamic functional connectivity changes associated with psychiatric traits and…

For a short and thin teenager in Poland, his case of Cushing’s disease was first seen as osteoporosis, a condition that causes bones to become weak and prone to fracture. The boy, 15 at the time of diagnosis, did not show other typical …

Cushing’s disease caused by Crooke cell adenoma — a rare but typically more aggressive pituitary tumor — is less likely than forms of the disease associated with other types of pituitary tumors to go into remission in the months following surgery. This is true despite the fact that surgery…

A form of precise radiation therapy, called intensity-modulated radiation therapy (IMRT), may be safe and effective for Cushing’s disease when a tumor in the brain’s pituitary gland has not been completely removed or has returned after surgery, a study suggests. The study, “Intensity-modulated radiotherapy for cushing’s disease:…

A woman developed Cushing syndrome after four months of taking supplements that contained a steroid, which she was not aware of because the supplement did not mention it on its label, according to a case report. “This case highlights the importance of educating patients to exercise caution when purchasing health…