News

A 70-year-old woman with ectopic Cushing’s syndrome was successfully treated for COVID-19 with intravenous immunoglobulins (IVIg) — a therapy prepared from the blood of thousands of healthy donors that contains a mixture of antibodies — according to a case report. Given the lack of guidelines for the management of…

The case of a woman with Cushing’s syndrome whose symptoms included eyelid edema — swelling of the upper eyelids — was described in a recent report. Its authors described eyelid edema is “a significant sign” of Cushing’s, but also noted the symptom “has scarcely been reported in countries other than…

Removing a pituitary tumor through the nostrils with an endoscope led to shorter recovery times for patients with Cushing’s disease than for those who had the surgery through the traditional microscopic approach, a study reports. However, similar remission, recurrence, and complication rates were found between patients, regardless of the…

Nonprofits, scientists, governmental organizations, and the rare disease drug development industry have long cited 7,000 as the average number of rare diseases in the world. But a new analysis shows there are as many as 10,867 rare diseases globally. And that…

A man with a known history of human immunodeficiency virus (HIV) infection and asthma developed Cushing’s syndrome after taking Tybost (cobicistat) together with fluticasone, according to a report from Spain. Tybost is a antiretroviral medicine booster, while fluticasone is a corticosteroid. The condition occurred because Tybost slows down how fast…

A minimally invasive chest surgery using a single-incision subxiphoid approach was used to effectively remove a tumor in the thymus of a 29-year-old woman with ectopic Cushing’s syndrome, as described in a recent case report. The muscle-sparing incision causes less trauma and potentially could reduce post-surgical pain and shorten recovery…

Metopirone (metyrapone) and Isturisa (osilodrostat) were both effective at controlling cortisol levels in people with endogenous Cushing’s syndrome over a 12-week period, according to a recent study. However, Isturisa tended to lower cortisol levels faster, and appeared to be better at controlling blood pressure than Metopirone. Some heart…

Hard-to-treat psychosis can be one of the first signs of Cushing’s disease, according to researchers in Saudi Arabia who detailed the case of a young woman with the disorder who was initially misdiagnosed. The 22-year-old patient “presented to a psychiatry hospital before being referred to us because she resisted…

Children and adolescents with Cushing’s disease who have subclinical bleeding near their disease-driving tumors may respond differently to tests used to diagnose the disease, compared with patients without this bleeding, according to a new study. These differences may complicate the diagnostic workup of these patients and “should be incorporated…

For people with Cushing’s disease who have pituitary tumors that are not visible by MRI, careful exploratory surgery coupled with initial analyses to identify the location of a tumor can be used to achieve remission, a new study highlights. “The rate of MRI-negative [tumors] is reported to be between…