The 2008 Endocrine Society Practice guideline remains a valid tool for defining the clinical signs and at-risk groups that should undergo screening for Cushing’s syndrome, according to a 10-year prospective German study. However, while 73% of the Cushing’s diagnoses were made in the at-risk groups defined by the guideline, the…
News
A 70-year-old woman with ectopic Cushing’s syndrome was successfully treated for COVID-19 with intravenous immunoglobulins (IVIg) — a therapy prepared from the blood of thousands of healthy donors that contains a mixture of antibodies — according to a case report. Given the lack of guidelines for the management of…
The case of a woman with Cushing’s syndrome whose symptoms included eyelid edema — swelling of the upper eyelids — was described in a recent report. Its authors described eyelid edema is “a significant sign” of Cushing’s, but also noted the symptom “has scarcely been reported in countries other than…
Removing a pituitary tumor through the nostrils with an endoscope led to shorter recovery times for patients with Cushing’s disease than for those who had the surgery through the traditional microscopic approach, a study reports. However, similar remission, recurrence, and complication rates were found between patients, regardless of the…
Nonprofits, scientists, governmental organizations, and the rare disease drug development industry have long cited 7,000 as the average number of rare diseases in the world. But a new analysis shows there are as many as 10,867 rare diseases globally. And that…
A man with a known history of human immunodeficiency virus (HIV) infection and asthma developed Cushing’s syndrome after taking Tybost (cobicistat) together with fluticasone, according to a report from Spain. Tybost is a antiretroviral medicine booster, while fluticasone is a corticosteroid. The condition occurred because Tybost slows down how fast…
A minimally invasive chest surgery using a single-incision subxiphoid approach was used to effectively remove a tumor in the thymus of a 29-year-old woman with ectopic Cushing’s syndrome, as described in a recent case report. The muscle-sparing incision causes less trauma and potentially could reduce post-surgical pain and shorten recovery…
Metopirone (metyrapone) and Isturisa (osilodrostat) were both effective at controlling cortisol levels in people with endogenous Cushing’s syndrome over a 12-week period, according to a recent study. However, Isturisa tended to lower cortisol levels faster, and appeared to be better at controlling blood pressure than Metopirone. Some heart…
Hard-to-treat psychosis can be one of the first signs of Cushing’s disease, according to researchers in Saudi Arabia who detailed the case of a young woman with the disorder who was initially misdiagnosed. The 22-year-old patient “presented to a psychiatry hospital before being referred to us because she resisted…
Children and adolescents with Cushing’s disease who have subclinical bleeding near their disease-driving tumors may respond differently to tests used to diagnose the disease, compared with patients without this bleeding, according to a new study. These differences may complicate the diagnostic workup of these patients and “should be incorporated…
Recent Posts
- The challenges of managing Cushing’s disease during the postpartum period
- Test may be ‘practical’ alternative for diagnosing Cushing’s in kids
- Man’s aggressive salivary gland cancer triggers Cushing’s syndrome: Report
- FDA rejects relacorilant for Cushing’s-related high blood pressure
- Study supports Isturisa as first-line ectopic Cushing’s treatment
- After some scary complications, I finally gave birth to a baby girl
- Rare dual diagnosis explains man’s chronic high blood pressure: Report
- Woman with recurrent Cushing’s disease has 2 successful pregnancies
- Real-world study backs Isturisa for non-pituitary Cushing’s forms
- New research shows Cushing’s adds hidden fat BMI may overlook