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Chronic insomnia can be a sign of Cushing’s syndrome, and doctors need be aware of this possibility, according to a case report of a woman diagnosed with Cushing’s shortly after seeking help for her insomnia. This case also emphasized the usefulness of the dexamethasone suppression test in identifying the specific…

A woman with a rare case of Cushing’s disease, in which rising cortisol triggered the production of yet more cortisol, may represent a new subtype of the disorder. She was the focus of the recent case report “Tumor shrinkage by metyrapone in Cushing’s disease exhibiting glucocorticoid-induced…

Screening for endocrine disorders, such as Cushing’s syndrome, is particularly important in patients who have tumors in hormone-producing endocrine glands, such as the thyroid. This was the take-home message of a recent case report study that described the case of a woman with thyroid cancer who also had Cushing’s driven…

Cushing’s syndrome may increase the risk of acute pancreatitis, a condition in which the pancreas becomes inflamed suddenly, according to a recent case report. The study, “Acute pancreatitis associated with Cushing syndrome – A case report and literature review…

More than half of the people with rare diseases and their caregivers, asked in a survey, were undecided or less than willing to be vaccinated for COVID-19 if a vaccine was approved under emergency use authorization instead of the routine process, the EveryLife Foundation for Rare Disease reports. These findings…

Clinical outcomes of COVID-19 in people with Cushing’s syndrome seem to depend on the severity of hypercortisolism, or how high blood cortisol levels are in these patients, according to a recent case series study. “Severe hypercortisolism is a warning sign that [Cushing’s syndrome] affected by COVID-19…

The EveryLife Foundation for Rare Diseases is accepting applications for a scholarship program that aims to help adults with a rare disease pursue personal goals through training and education. For a second year, the #RAREis Scholarship Fund — supported by Horizon Therapeutics – will award 35 one-time scholarships, each…

Cortisol fluctuations in a woman with Cushing’s disease were controlled successfully with Signifor (pasireotide LAR), possibly for the first time, according to a recent case report. The report, “Resolution of cyclicity after pasireotide LAR in a patient with Cushing’s disease,” was published in the journal…

Recorlev (levoketoconazole), Strongbridge Biopharma’s oral investigational therapy for endogenous Cushing’s syndrome, led to sustained improvements in cortisol and in blood sugar control among patients with both Cushing’s and diabetes, a subgroup analysis of Phase 3 SONICS trial data showed. “Diabetes mellitus [type 1 diabetes] is among the…

Although mortality rates associated with endogenous Cushing’s syndrome have dropped in recent years, the disease is still linked to a threefold increase in the risk of death, mainly from cardiovascular issues and infections, a recent analysis of past research has found. “Our results found that death rates have fallen…