News

In people with Cushing’s disease, the activity of an enzyme that breaks down vitamin D is altered, which may affect the effectiveness of vitamin D dietary supplements, according to a new study. The study, “Assessment of Vitamin D Metabolism in Patients with Cushing’s Disease in Response…

When placed over the skin, potent corticosteroids induced Cushing’s syndrome in an infant who was given the medications over a long period of time to treat diaper rash, a recent case study reported. “Physicians need to consider this in infantile [Cushing’s syndrome] cases, and take appropriate measures to avoid…

The case of an elderly woman who may have developed Cushing’s syndrome due to a hormone-producing lump in her lungs highlights the need for a timely and “multidisciplinary approach in [the] diagnosis and management” of hypercortisolism disorders, according to a new report. This patient’s signs and symptoms progressed…

The desmopressin stimulation test can be useful to diagnose Cushing’s during pregnancy, a time when its identification may be particularly challenging due to the hormonal changes these women experience, a new case report says. The report, “Desmopressin Stimulation Test in a Pregnant Patient with Cushing’s Disease,” was published…

Scientists have decoded molecular processes of a gene whose defects are implicated in Cushing’s disease and some cancers. Their study found that mutations in the ubiquitin-specific protease 8 (USP8) gene prevent a self-suppressing mechanism of the resulting enzyme, leading to its overactivation. Overactivation of this enzyme has been shown…

A combination of two easily performed tests reached 100% accuracy for diagnosing Cushing’s disease in people with an initial negative result from an MRI scan, or who had a a small tumor in their brain’s pituitary gland, a study reports. The study, “Indication to dynamic and…

Cushing’s syndrome may develop in people with advanced medullary thyroid cancer and is associated with a poor prognosis, a retrospective analysis suggests. Severely low levels of potassium in the blood, muscle weakness, and/or diabetes in medullary thyroid cancer patients are signs of ectopic Cushing’s. The case-series study, titled “…

In a rare case, a hormone-producing intestinal tumor led to the development of ectopic Cushing’s syndrome in a 50-year-old man, according to a recent report. The patient’s high cortisol levels — a hallmark of hypercortisolism — normalized after he underwent surgery to remove both adrenal glands, which are responsible for…

Over 230 national organizations signed a letter urging all 50 U.S. state governors to “maintain and expand” flexibility with licensure requirements for the duration of the COVID-19 pandemic to ease access to care. During the pandemic, governors used emergency authority to waive certain state licensure requirements, giving healthcare providers…

Cushing’s disease was successfully treated using metyrapone in a pregnant women with no harm to the unborn baby, a case-report found. The report, “Cushing Disease Treated Successfully with Metyrapone During Pregnancy,” was published in the journal AACE Clinical Case Reports. Cushing’s syndrome is characterized by excessive levels of…