News

Although mortality rates associated with endogenous Cushing’s syndrome have dropped in recent years, the disease is still linked to a threefold increase in the risk of death, mainly from cardiovascular issues and infections, a recent analysis of past research has found. “Our results found that death rates have fallen…

From bolstering a list of recommended physicians to sharing patient stories, the Cushing’s Support & Research Foundation (CSRF) offers various ways for supporters to mark Cushing’s Awareness Day, taking place on April 8. The day is set aside annually to call attention to the more than 6 million people…

As anyone affected by a rare disease knows, treating the illness while trying to go about everyday life is an expensive undertaking.  But exactly how expensive — in terms of direct and indirect costs across rare disease populations — might still come as a surprise: almost…

The Japanese Ministry of Health, Labour and Welfare (MHLW) has approved Isturisa (osilodrostat) to treat people with endogenous Cushing’s syndrome for whom pituitary brain surgery has not been effective or is not an option. Recordati…

Recorlev (levoketoconazole), Strongbridge Biopharma’s oral candidate to treat endogenous Cushing’s syndrome, was superior to a placebo at lowering cholesterol levels and body mass index, a measure of body fat, according to newly released data from the pivotal Phase 3 LOGICS trial. These findings, concerning most of the trial’s…

Isturisa (osilodrostat), an approved oral therapy for Cushing’s disease, can rapidly normalize — in a median of 35 days — the levels of urine free cortisol in people with the disease, according to newly released data from the Phase 3 LINC-4 trial. Treatment also led to sustained improvements in…

Endoscopic transsphenoidal surgery (ETSS), a minimally invasive procedure that allows surgeons to remove pituitary tumors in people with Cushing’s disease, is associated with good remission rates, according to a recent study. The study, “Outcomes of endoscopic transsphenoidal surgery for Cushing’s disease,” was published in the journal BMC Endocrine…

HRA Pharma Rare Diseases is providing an unrestricted educational grant to fund “Cushing’s Hub,” a first-of-its-kind online platform designed to help healthcare providers care for patients with Cushing’s syndrome. The Hub, developed by Springer Healthcare Education, will provide information to promote good clinical practice, and improve diagnosis and…

People with Cushing’s syndrome are likely at a higher risk of developing atrial fibrillation, a condition that causes the heart to beat at an irregular — and usually faster — pace, according to a review study. The review also found that…

Although rare, Cushing’s disease associated with a tumor in the pituitary gland — a pea-size gland found deep within the brain — may occur in patients who also have a meningioma, a type of tumor that arises from the membranes that cover the brain within the skull, a case…