More biomarkers needed to support Cushing’s syndrome diagnosis

More biomarkers are necessary for the differential diagnosis of Cushing’s syndrome subtypes in children and adolescents, as well as to predict disease progression more effectively — allowing for quicker and less invasive assessments of patients. That’s according to the results of a new, large, observational study, which also reported on…

Metyrapone Rapidly Reduces Cortisol Levels in Cushing’s Syndrome Patients, Real-Life Study Shows

Treatment with metyrapone rapidly reduces cortisol levels in Cushing’s syndrome patients and keeps them low over the long term, a real-life study shows. The study, “Metyrapone treatment in Cushing’s syndrome: a real-life study,” was published in the journal Endocrine. Cushing’s syndrome is a condition where patients have too much cortisol…

Adrenal Crisis Not a Major Cause of Death in Cushing’s Patients with Adrenal Insufficiency

Cushing’s syndrome patients who have adrenal insufficiency have increased risk of death due to disease-related complications, rather than adrenal crisis or adverse occurrences, an observational study suggests. The study, “Mortality data from the European Adrenal Insufficiency Registry—Patient characterization and associations,” was published in the journal Clinical…