Posts by: Alice Melao

News

Relacorilant, an investigational therapy developed by Corcept Therapeutics, may effectively manage the effects of excess cortisol in patients with Cushing’s syndrome, interim data from an ongoing Phase 2 trial show. ... Read more

May 4, 2018

Rare Malignant Tumor of Adrenal Gland Led to Cushing’s, Girl’s Death, Case Report Shows

News

While adrenocortical carcinoma — a malignant tumor of the adrenal gland — appears only rarely in children, the tumor may cause secondary Cushing’s syndrome in these patients, a new ... Read more

May 3, 2018May 3, 2018

Cushing’s Patient Exhibits Cortisol-Secreting Lesions in Both Adrenal Glands

News

In rare cases, Cushing’s syndrome may be caused by cortisol-secreting masses in both adrenal glands, a case report shows. The study with that finding, “ACTH-independent Cushing’s syndrome with bilateral ... Read more

April 17, 2018

Phase 2 Trial Testing Seliciclib for Cushing’s Disease Is Recruiting Participants

News

A new Phase 2 trial evaluating the promising investigative therapy seliciclib as a treatment for Cushing’s disease is currently enrolling participants. The trial (NCT02160730), at Cedars-Sinai Medical Center in Los Angeles, will ... Read more

April 5, 2018

Strongbridge Starts Another Phase 3 Trial of Its Cushing’s Therapy

News

Strongbridge Biopharma has begun dosing patients in another Phase 3 clinical trial of its Cushing’s syndrome therapy Recorlev (levoketoconazole). The company will enroll roughly 35 patients in the LOGICS (NCT03277690). Those participating in ... Read more

March 13, 2018March 13, 2018

Mild Cortisol Increases Affect Cardiovascular Changes Linked to Heart Disease in Cushing’s

News

Increases in cortisol secretion, even if mild, induce early heart and blood vessel changes that may increase the risk for cardiovascular disease, according to Italian researchers. The findings continue ... Read more

March 9, 2018March 9, 2018

Steroid Medication for Nasal Obstruction in Infants May Cause Cushing’s Syndrome, Study Shows

News

Intranasal steroid drops used to treat nasal obstruction may cause Cushing’s syndrome and adrenal insufficiency in infants, a case study of two patients suggests. The study, “Iatrogenic Cushing’s syndrome and ... Read more

March 8, 2018March 8, 2018

Case Report Shows Rare Adrenal Tumors Associated with Cushing’s Disease

News

Pituitary tumors that produce too much adrenocorticotropic hormone (ACTH) have been associated with the development of rare tumors on the adrenal glands, called adrenal myelolipomas, for the first time in ... Read more

March 6, 2018

Cushing’s Patients at Risk for Autoimmune Diseases After Condition Is Resolved, Study Says

News

Children with Cushing’s syndrome are at risk of developing new autoimmune and related disorders after being cured of the disease, a new study shows. The study, “Incidence of Autoimmune ... Read more

January 25, 2018January 28, 2018

Frequent Use of Topical Steroid to Treat Diaper Rash Led to Cushing Syndrome, Case Study Reports

News

Excessive use of skin-applied steroids to manage diaper rash can lead to an infant developing Cushing’s syndrome, a case study reports. Cushing’s is characterized by elevated levels of hormones ... Read more