Nearly one out of four people with difficult-to-treat type 2 diabetes also has Cushing’s syndrome, according to preliminary data from the Phase 4 CATALYST clinical trial. “These results are very powerful,” Ralph DeFronzo, MD, an investigator on the CATALYST study and professor of medicine at UT Health San Antonio,…
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A report detailed the rare case of a woman whose Cushing’s syndrome quickly developed as a result of a silent pheochromocytoma — a rare adrenal gland tumor — that produced and released both corticotropin-releasing hormone (CRH) and adrenocorticotropic hormone (ACTH). The report, “Cushing Syndrome due to a…
Feelings of loneliness and hopelessness affect the majority of people with Cushing’s disease, according to a survey conducted by the Memorial Sloan Kettering (MSK) Cancer Center in New York. Patients often felt they had no choices about their treatment, which contrasted with the perception of healthcare providers at MSK’s…
Psychosis may be more common with Cushing’s disease than previously thought, according to a recent U.S. case report about a 47-year-old woman who had surgery to remove a pituitary tumor, but whose signs of psychosis weren’t evident to her hospital team in the months before the procedure. “This…
The rare case of Cushing’s syndrome due to a cortisol-producing adrenal tumor and acromegaly that resulted from a growth-hormone-producing tumor in the pituitary gland was described in a recent report. Acromegaly occurs when the pituitary gland produces excessive amounts of growth hormone during adulthood, resulting in…
Isturisa (osilodrostat) was able to successfully treat ectopic Cushing’s syndrome due to a lung tumor in a 68-year-old man with lung cancer, according to a recent case report. Treatment led to a reduction in the patient’s blood cortisol levels, which were elevated as a result of the lung tumor…
Singapore’s Health Sciences Authority (HSA) has issued a warning that Gu Jie Ling, an herbal concoction marketed as a “traditional medicine,” contains a drug called dexamethasone that can cause Cushing’s syndrome, and has advised the public not to purchase or consume it. The HSA recommends that people who have…
A 66-year-old woman developed exogenous Cushing’s syndrome — when the disease is unintentionally caused by medications — after accidentally taking a glucocorticoid prescribed for her husband, according to a case report. Exogenous Cushing’s syndrome is the most common form of the condition, but usually is triggered by the use…
Two unusual cases of Cushing’s syndrome caused by pancreatic tumors that had spread to the liver were described in a recent report, highlighting the importance of assessing the presence of Cushing’s in people with pancreatic tumors who continue to show signs of the disorder. The disorder, called ectopic ACTH syndrome…
A survey of U.S. doctors treating people with Cushing’s syndrome noted a considerable burden of symptoms, ranging from fatigue to muscle weakness, that weigh on patients’ life quality and personal finances, and a need for better treatments. These endocrinologists — physicians who specialize in disorders affecting hormone-producing glands — also…
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