Metformin, a medicine used mostly to treat type 2 diabetes, eased the signs of Cushing’s disease in cells and in a mouse model, a study showed. “These findings suggest metformin as a potential drug for the treatment of Cushing’s disease,” researchers wrote in the study, “Metformin…
News
The first symptoms of Cushing’s syndrome due to a neuroendocrine tumor in the right lung were severe psychiatric manifestations, including persecutory delusions, depression, and anxiety, for a man described in a recent case report from Tunisia. The case highlights that “[Cushing’s syndrome] should be considered by…
A 27-year-old woman in China has become the first reported case of an adult developing ectopic Cushing’s syndrome as a result of a rare yolk sac tumor in the pancreas producing high levels of adrenocorticotropic hormone (ACTH) precursors, according to researchers. A yolk sac tumor is a rare, malignant tumor…
In 2023, Cushing’s Disease News brought readers comprehensive coverage of the latest scientific research and developments in treatment for Cushing’s disease. Here are the 10 most-read news stories of 2023, along with a brief description of each. We look forward to continuing to serve as a resource for…
Accurately locating tumors in the brain’s pituitary gland by inferior petrosal sinus sampling or IPSS — an invasive test that’s been considered the gold standard for diagnosing Cushing’s disease — may not necessarily lead to better outcomes after surgery, according to a new meta-analysis. While IPSS correctly determined…
Surgery to remove adrenal tumors without taking the entire adrenal gland — given to Cushing’s syndrome patients to lower cortisol levels — associated with better outcomes than surgeries that remove all of the adrenal gland, a study reports. Benefits included a shorter period of dependency on corticorteroids after surgery and…
A 32-year-old woman with a rare case of two pituitary tumors required two surgeries to treat her Cushing’s disease, according to a recent report. Her disease was caused by one tumor, or adenoma, that resulted in high amounts of the adrenocorticotropic hormone (ACTH). The other tumor, called a prolactinoma, causes…
Cushing’s syndrome in a 45-year-old woman was complicated by primary aldosteronism, the result of tumors in the adrenal glands secreting both cortisol and aldosterone, according to a case reported in China. Aldosteronism occurs when the adrenal glands produce high levels of aldosterone, a hormone that regulates blood pressure and balances…
An 81-year-old woman being treated for a severe and persistent electrolyte imbalance was found to have a tumor in her lung which eventually led to her diagnosis of ectopic Cushing’s syndrome, according to a case report. Electrolytes are minerals in body fluids that carry an electric charge and are vital…
A woman with Cushing’s syndrome developed an ulcer that caused a gastrointestinal perforation, or a hole in the digestive tract, according to a case study. Because she had no established risk factors for such a complication, researchers suggested prolonged exposure to high levels of cortisol, or hypercortisolism, may have contributed…
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