Endoscopic transsphenoidal surgery, which allows a surgeon to gain access to the brain through the nose to remove a pituitary tumor causing Cushing’s disease, was found to be safe and effective for bringing about remission in children, with few complications. While this surgery is usually done in adults with…

A young woman with Cushing’s disease and acromegaly — marked by the abnormal growth of certain body parts due to pituitary gland dysfunction — saw her symptoms ease after undergoing surgery to remove a large hormone-producing tumor that caused both rare conditions, a study from Bangladesh reported. “The…

Blood levels of cortisol or adrenocorticotropic hormone (ACTH) measured one day after pituitary tumor removal surgery independently predicted Cushing’s disease remission after one year, according to a real-world study. Post-surgical remission rates were higher among adults after a first surgery compared with those seen for patients who underwent a second…

About 80% of people with recurrent Cushing’s disease who underwent a second surgery to remove tumors from the brain’s pituitary gland achieved remission, according to a real-world study. These findings show that repeat surgery “emerges as a reliable and safe treatment modality for residual or recurrent Cushing’s disease, offering…

About 1 in 4 people with Cushing’s syndrome caused by a tumor saw their symptoms come back after undergoing surgery to remove the tumor, a new study found. People with Cushing’s disease, which is caused by a pituitary tumor, saw their tumors recur sooner than did those whose…

Psychosis may be more common with Cushing’s disease than previously thought, according to a recent U.S. case report about a 47-year-old woman who had surgery to remove a pituitary tumor, but whose signs of psychosis weren’t evident to her hospital team in the months before the procedure. “This…

Surgery can partially reverse functional impairments in brain networks in people with Cushing’s disease after three months, when their cortisol levels return to normal, according to a recent study. Researchers say elevated cortisol levels in patients with active disease are linked to connectivity impairments in three large-scale functional brain…

Cushing’s disease caused by Crooke cell adenoma — a rare but typically more aggressive pituitary tumor — is less likely than forms of the disease associated with other types of pituitary tumors to go into remission in the months following surgery. This is true despite the fact that surgery…

Surgery to remove a tumor in the brain’s pituitary gland is effective in patients 75 years or older, including those with Cushing’s disease, and is associated with a low rate of complications, according to a study in France. The surgery was generally performed using a minimally invasive procedure and…

Dexamethasone suppression did not improve the detection of pituitary tumors via the use of PET, or positron emission tomography, scans in adults with Cushing’s disease, a new study has found. In most cases, using imaging tests to determine tumor location before pituitary surgery — the first-line treatment for Cushing’s…