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Bone tissue death successfully treated in man, 71, with Cushing’s

A 71-year-old man with Cushing’s disease developed avascular necrosis in the hips and shoulders, a condition in which bone tissue dies due to lack of blood supply, a U.S. case study reports. His Cushing’s symptoms, including avascular necrosis in the hips, were successfully managed with surgery to remove the…

Cushing’s symptoms secondary to tumor ease with Isturisa

A young woman who developed Cushing’s syndrome three years after being diagnosed with a metastatic neuroendocrine tumor saw her cortisol levels decrease and Cushing’s-related symptoms ease after being treated with Isturisa (osilodrostat). The woman, 27, was started on hydrocortisone when here cortisol levels fell to lower than normal values,…

Symptoms worsen with increasing cortisol levels in Cushing’s disease

People with Cushing’s disease may have higher levels of cortisol and more severe symptoms than those with other forms of Cushing’s, according to a recent study in Turkey. “The severity of disease symptoms worsens with increasing cortisol levels,” researchers wrote. The study, “Metabolic, hormonal profiles and comorbidities in…