Asymptomatic Cushing’s syndrome alongside primary hyperaldosteronism, or PHA — a disorder marked by excessive secretion of the hormone aldosterone — was found to be the cause of persistent, hard-to-treat high blood pressure in a 57-year-old man, according to a new case study. The research team, from Iran, noted the “diagnostic…
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A woman with persistent Cushing’s disease experienced two back-to-back pregnancies without significant problems for the mother or baby, a case study reported. “There are a limited number of cases of Cushing’s [disease] in pregnancy, therefore the best possible treatment is difficult to determine and should be individualised to the…
Isturisa (osilodrostat) can safely reduce, or even normalize, cortisol levels in people with various forms of endogenous Cushing’s syndrome that are not Cushing’s disease, according to data from a real-world study in France. The study, “Real-world osilodrostat effectiveness and safety in non-pituitary Cushing syndrome,” was…
Children with Cushing’s disease tend to have more total body fat than other children their age, even when their body mass index (BMI) is the same, a new study suggests. The study also found that detailed body-composition scans were better than BMI at predicting risks for issues such as…
Despite taking Isturisa (osilodrostat), a medication not recommended during pregnancy, a 38-year-old woman in Japan with recurrent Cushing’s disease carried a healthy baby through the first trimester, according to a newly published case report. After the pregnancy was discovered at 16 weeks, doctors immediately discontinued Isturisa. The woman’s…
When standard procedures fail, doctors may still be able to diagnose Cushing’s disease by sampling blood from veins near the pituitary gland using a catheter inserted through the neck — an alternative approach described in a new case report. The study, “Ultrasound-Guided Jugular Vein Access for…
A 43-year-old woman with Cushing’s disease developed an unusual sequence of psychiatric complications after rapid increases in her oral cortisol-lowering medication Isturisa (osilodrostat), a new case report from Japan shows. The woman first experienced a sudden worsening of her depression symptoms early in treatment, likely due to a transient rise…
Persistent symptoms during corticosteroid tapering should prompt evaluation for an internal source of excess cortisol — usually from the adrenal glands above the kidneys — because exogenous steroid use can mask signs of Cushing’s syndrome that the body is producing on its own. That’s what happened in the case…
Effective treatment, either surgical or using medications, significantly eased anxiety and depression, and improved quality of life, in some people with Cushing’s syndrome, according to the findings of a new U.S. study. However, when looking at treatment type, only patients who underwent surgery to remove tumors showed a statistically significant…
A woman with Cushing’s disease developed overlapping heart symptoms, a case researchers said highlights the need for early diagnosis and coordination between cardiologists and endocrinologists. The woman had cortisol-induced heart failure with preserved ejection fraction, meaning her heart pumped normally but was too stiff to fill properly. The heart…
Recent Posts
- Rare dual diagnosis explains man’s chronic high blood pressure: Report
- Woman with recurrent Cushing’s disease has 2 successful pregnancies
- Real-world study backs Isturisa for non-pituitary Cushing’s forms
- New research shows Cushing’s adds hidden fat BMI may overlook
- Isturisa exposure early in pregnancy may be less risky than thought
- Alternative neck access allows doctors to complete key test
- A pregnancy complication leads to yet another hospital admission
- Cushing’s patient’s psychiatric shifts tied to rapid Isturisa dose increase
- Years may pass by, but what I’m thankful for never changes
- Rare ‘double Cushing’s’ case highlights need to check cortisol