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December 13, 2018

Ultrasounds Useful in Detecting Muscle Problems from Steroid Myopathy, Study Says

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Ultrasound scans can be useful to monitor muscle changes in patients with glucocorticoid-induced muscle disease or steroid myopathy, and could become an effective routine procedure for those with Cushing’s disease, ... Read more

December 6, 2018

Case Series Highlights Importance of Recognizing Discrepancies Between ACTH Blood Results and Clinical Data

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Recognizing discrepancies between blood tests of adenocorticotropic hormone (ACTH) levels and patients’ clinical data is important for clinicians to avoid unnecessary testing or misdiagnosis, a case series highlights. The study, ... Read more

December 4, 2018December 4, 2018

1st Patient Dosed in Phase 3 Trial of Relacorilant to Treat Cushing’s Syndrome

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A first patient has been dosed in a Phase 3 trial testing relacorilant as a possible treatment for Cushing’s syndrome, the investigative treatment’s maker, Corcept Therapeutics, announced a press release. The trial, called ... Read more

November 29, 2018

Survey Gathers Support Needs of Cushing’s Syndrome Patients in U.S., Germany

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Competent physicians and long-term medical care are the types of support that most help patients with Cushing’s syndrome cope with their condition, a patient-reported survey in the U.S. and ... Read more

November 27, 2018

Levels of Certain Hormones May Predict Malignancies in Adrenal Tumors in Children, Study Suggests

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Higher levels of sex corticosteroid hormones — such as testosterone — and an enzyme called lactate dehydrogenase may predict malignancies of adrenal masses in children, according to a study. Findings ... Read more

November 20, 2018

Mutations in Two Genes, USP48 and BRAF, Linked to Cushing’s Disease in Study

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Mutations in USP48 and BRAF genes contribute to the overproduction of adrenocorticotropin (ACTH) hormone by the pituitary gland and consequent development of Cushing’s disease, a study shows, linking these ... Read more

November 15, 2018

Metopirone Normalizes Cortisol Levels, Improves Clinical Parameters in Cushing’s Patients When Used Pre-Surgery, Study Finds

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Pre-surgery treatment of adrenocorticotropic hormone (ACTH)-independent Cushing’s syndrome with Metopirone (metyrapone) leads to effective and safe improvement of hormonal levels and clinical parameters, according to a new pilot study. The research, ... Read more

November 13, 2018

Low-dose Use of Chemotherapy, Lysodren, May Treat Children Ineligible for Surgery, Study Reports

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Low-dose Lysodren (mitotane) can help restore growth rates and pubertal development, and lower body mass index (BMI) in children with Cushing’s disease who are not eligible for pituitary surgery. ... Read more

November 8, 2018November 8, 2018

Measuring Pituitary Gland Hormone with BIPSS in Children Not as Accurate as Previously Thought, Study Finds

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Bilateral inferior petrosal sinus sampling (BIPSS) — a diagnostic technique for Cushing’s disease that measures the levels of the adrenocorticotropic hormone (ACTH) hormone produced by the pituitary gland — is not as accurate ... Read more

November 6, 2018

FDA Approves High-resolution MRI, Better at Spotting Pituitary Tumors in Cushing’s Patients

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The U.S. Food and Drug Administration has approved the clinical use of a magnetic resonance imaging (MRI) scanner — the ultra-high-field 7T Terra MRI — with unprecedented resolution that ... Read more

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