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October 16, 2018

Rare Prostate Cancer Associated with Cushing’s Syndrome in Case Report

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A patient with depression developed Cushing’s syndrome (CS) because of a rare ACTH-secreting small cell cancer of the prostate, a case study reports. The case report, “An unusual cause ... Read more

October 12, 2018

Keytruda Found Ineffective in Rare Case of Adrenal Cancer Caused by Lynch Syndrome, Report Shows

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Keytruda (pembrolizumab) may not be effective in Lynch syndrome patients — those with inherited mutations in certain DNA repair genes — who develop Cushing’s syndrome due to cortisol-secreting metastatic ... Read more

October 11, 2018

Most Subclinical Cushing’s Patients Don’t Require Glucocorticoids After Adrenalectomy, Study Finds

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Patients with subclinical hypercortisolism, i.e., without symptoms of cortisol overproduction, and adrenal incidentalomas recover their hypothalamic-pituitary-adrenal (HPA) axis function after surgery faster than those with Cushing’s syndrome (CS), according to ... Read more

October 10, 2018October 9, 2018

Advocacy Groups, Doctors Question Rising Prices of Rare Disease Treatments

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Half a year has gone by since disgraced pharma executive Martin Shkreli was sentenced to seven years in federal prison for securities and wire fraud while heading San Diego-based ... Read more

October 9, 2018

Cushing’s-derived Insulin Resistance Driven by Macrophages in Gonadal Adipose Tissue, Study Reports

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A type of immune cell called a macrophage in the gonadal fat tissue may be key in glucocorticoid-induced insulin resistance in patients with Cushing’s syndrome, according to a mouse ... Read more

October 4, 2018

Ectopic Cushing’s Linked to Rare Head and Neck Cancer in Case Study

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A patient was diagnosed with Cushing’s syndrome caused by a very rare cancer known as small cell carcinoma of the uvula — the small tissue that hangs at the back ... Read more

October 2, 2018

Adrenal Venous Sampling Helps Surgical Decisions in Type of Cushing’s, Study Suggests

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Cushing’s syndrome patients with tumors on both adrenal glands — which sit on top of the kidneys — could undergo adrenal venous sampling, a procedure where blood samples are taken ... Read more

September 28, 2018September 28, 2018

Bilateral Adrenalectomy Negatively Affects Quality of Life in Cushing’s Patients, Study Suggests

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Bilateral adrenalectomy, in which the adrenal glands are removed, has a bigger negative impact on the quality of life of patients with Cushing’s disease than other treatment options, a ... Read more

September 27, 2018

Fluconazole Found to Be Safe Alternative for Patient with Recurrent Cushing’s, Case Report Shows

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Treatment with fluconazole after cabergoline eased symptoms and normalized cortisol levels in a patient with recurrent Cushing’s disease who failed to respond to ketoconazole, a case study reports. The case ... Read more

September 21, 2018September 21, 2018

Pregnancy Could Be Linked to Onset of Cushing’s Symptoms, Retrospective Study Suggests

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More than 25 percent of women with Cushing’s disease experienced their first symptoms within one year of giving birth, a small study by the Pacific Neuroscience Institute found. The findings suggest ... Read more

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