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September 19, 2019

Psychiatric Symptoms Related to Cushing’s Disease May Include Delusions, Case Report Suggests

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Delusions — fixed beliefs that do not change even when confronted with refutable evidence — are among the mental manifestations that can be primary symptoms of Cushing’s disease, a ... Read more

September 17, 2019

Global Real-world Study Supports Signifor’s Long-term Benefits

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Data from an ongoing real-world study show that treatment with Signifor (pasireotide) is able to normalize cortisol levels for sustained periods in patients with Cushing’s disease for whom surgery ... Read more

September 12, 2019

Adrenal Gland Transplants Show Long-term Efficacy in Refractory Cushing’s Disease, Study Reports

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Adrenal gland transplants resulted in complete resolution of Cushing’s disease symptoms after no long-lasting benefits were seen with pituitary surgery, according to a new long-term study in four patients. ... Read more

September 10, 2019

Drug Interactions Cause Worse Cushing’s Symptoms in HIV Patients, Study Finds

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People living with HIV who develop Cushing’s syndrome due to drug interactions tend to have more severe symptoms than non-infected people, a study found. The study, “Cushing’s syndrome due ... Read more

September 5, 2019

Fluconazole Is Potential Treatment for Severe Cushing’s Syndrome, Case Report Contends

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Fluconazole — a treatment for fungal infections that can lower cortisol levels — could be a potential therapy for severe Cushing’s syndrome caused by ACTH-secreting tumors located outside the ... Read more

September 3, 2019

U.S. Patent to Cover Korlym Administration with Food, Corcept Announces

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The administration with food of the Cushing’s syndrome therapy Korlym (mifepristone) will be covered by a new U.S. patent, according to Corcept Therapeutics – the company marketing Korlym. Upon ... Read more

September 2, 2019August 30, 2019

‘Disorder’ Film Festival Offers Look at Siblings Touched by Rare Diseases

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Rare diseases deeply affect not only the children who experience them, but also their healthy brothers and sisters, as their parents can attest. Two entries in November’s “Disorder: ... Read more

August 29, 2019

ACTH Levels After Surgery Help Predict Remission, Recurrence in Cushing’s, Study Suggests

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Levels of adrenocorticotropic hormone (ACTH) in circulation after pituitary surgery may help predict which Cushing’s disease patients will achieve early remission and which will eventually see the disease return, ... Read more

August 28, 2019

At NY Genome Center, Legal Expert Presents Ethical Dilemmas in Gene Editing

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Developing gene therapies for rare diseases is one thing. Creating gene-edited “designer babies” is quite another. German legal expert Timo Minssen outlined the potentially explosive ethical landmines surrounding such ... Read more

August 27, 2019

Degree of Fat in Bone Marrow Ably Judges Fracture Risk in Cushing’s Patients, Study Suggests

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Measures of the degree of fat in bone marrow could be a reliable marker of bone health, helping doctors to predict the risk of fractures in people with Cushing’s ... Read more

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