A higher volume of epicardial adipose tissue (EAT) — meaning more fat accumulated near the heart muscle and arteries that supply the heart — significantly increases the risk for early heart disease in people with Cushing’s syndrome. That’s according to a study from China that assessed risk factors for left…
News
The rare case of a 6-month-old girl in India who developed ectopic Cushing’s syndrome due to a cancerous tumor in her right hip was described in a new study. After completing two rounds of chemotherapy and undergoing surgery, the girl recovered normal functioning in her hypothalamic-pituitary-adrenal axis, which controls cortisol…
Women with Cushing’s syndrome may be misdiagnosed with fibromyalgia — a chronic condition characterized by widespread pain and mental distress — despite showing Cushing’s symptoms, a new case series report demonstrates. The researchers say these misdiagnoses of fibromyalgia, occurring in a trio of Cushing’s syndrome patients across three…
Treatment with Isturisa (osilodrostat) is generally well tolerated and effective at reducing cortisol levels and easing Cushing’s disease symptoms in Asian patients, with results similar to those seen in non-Asian patients. That’s according to a new study that compared both patient populations in two Phase 3 clinical trials…
A rare, highly malignant kidney tumor turned out to be the cause of Cushing’s syndrome in an 18-year-old man whose case was described in a recent study. The man had classic symptoms of Cushing’s, including weight gain, fat buildup, and skin changes that resolved after the kidney harboring the…
A new report from researchers at the Montefiore Medical Center in New York details the cases of two women with ectopic Cushing’s secondary to diffuse idiopathic neuroendocrine cell hyperplasia, or DIPNECH — a rare lung disease that may lead to the development of tumors that in extremely rare cases may…
Diagnosing and managing Cushing’s syndrome in children can be complex and takes careful management, according to a case report and review study that described the difficult diagnostic process for a boy who was ultimately found to have Cushing’s disease that could be managed through surgery. “Our case was illustrative…
A low-dose dexamethasone test, which is commonly used to diagnose Cushing’s syndrome, can effectively detect the rare condition in people with obesity, according to a new study. However, despite the test’s effectiveness, the proportion of patients who ultimately were diagnosed with Cushing’s was low, at 0.2%. Given that finding,…
People with Cushing’s disease have more fat in their kidneys and around the heart than those with other conditions with elevated cortisol, a study suggests. Across all the people evaluated, including those with Cushing’s syndrome, levels of these types of fat were associated with metabolic factors, such as diabetes,…
A diagnostic test using desmopressin, an artificial form of a naturally occurring hormone, can help to accurately identify people with Cushing’s disease, a study reports. Easier than the current gold standard for diagnosing this disease, the desmopressin stimulation test might “reduc[e] the reliance on invasive procedures and provid[e] a…
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