News

A survey of U.S. doctors treating people with Cushing’s syndrome noted a considerable burden of symptoms, ranging from fatigue to muscle weakness, that weigh on patients’ life quality and personal finances, and a need for better treatments. These endocrinologists  — physicians who specialize in disorders affecting hormone-producing glands — also…

Being male, having high cortisol levels at the time of Cushing’s diagnosis, and undergoing multiple surgeries were identified as key factors linked to a high risk of blood clots in people with Cushing’s, according to data from a large European registry. Preventive anti-blood clotting protocols varied across treatment centers,…

More biomarkers are necessary for the differential diagnosis of Cushing’s syndrome subtypes in children and adolescents, as well as to predict disease progression more effectively — allowing for quicker and less invasive assessments of patients. That’s according to the results of a new, large, observational study, which also reported on…

Metformin, a medicine used mostly to treat type 2 diabetes, eased the signs of Cushing’s disease in cells and in a mouse model, a study showed. “These findings suggest metformin as a potential drug for the treatment of Cushing’s disease,” researchers wrote in the study, “Metformin…

The first symptoms of Cushing’s syndrome due to a neuroendocrine tumor in the right lung were severe psychiatric manifestations, including persecutory delusions, depression, and anxiety, for a man described in a recent case report from Tunisia. The case highlights that “[Cushing’s syndrome] should be considered by…

A 27-year-old woman in China has become the first reported case of an adult developing ectopic Cushing’s syndrome as a result of a rare yolk sac tumor in the pancreas producing high levels of adrenocorticotropic hormone (ACTH) precursors, according to researchers. A yolk sac tumor is a rare, malignant tumor…

In 2023, Cushing’s Disease News brought readers comprehensive coverage of the latest scientific research and developments in treatment for Cushing’s disease. Here are the 10 most-read news stories of 2023, along with a brief description of each. We look forward to continuing to serve as a resource for…

Accurately locating tumors in the brain’s pituitary gland by inferior petrosal sinus sampling or IPSS — an invasive test that’s been considered the gold standard for diagnosing Cushing’s disease — may not necessarily lead to better outcomes after surgery, according to a new meta-analysis. While IPSS correctly determined…

Surgery to remove adrenal tumors without taking the entire adrenal gland — given to Cushing’s syndrome patients to lower cortisol levels — associated with better outcomes than surgeries that remove all of the adrenal gland, a study reports. Benefits included a shorter period of dependency on corticorteroids after surgery and…

A 32-year-old woman with a rare case of two pituitary tumors required two surgeries to treat her Cushing’s disease, according to a recent report. Her disease was caused by one tumor, or adenoma, that resulted in high amounts of the adrenocorticotropic hormone (ACTH). The other tumor, called a prolactinoma, causes…