News

High blood-sugar levels and osteoporosis — a condition causing bones to weaken and be prone to fracture — are more common in men with ectopic Cushing’s syndrome than women, who are more likely to have high blood pressure, a Turkish study reports. “Apart from these, the lack of sex differences,…

The rare case of an 18-year-old woman with ectopic Cushing’s syndrome due to a neuroendocrine lung tumor — a rare tumor that may cause Cushing’s — was described by researchers at the Icahn School of Medicine at Mount Sinai in New York. The patient was successfully treated by surgically removing…

Sleep quality markedly improves for people with endogenous Cushing’s syndrome after treatment leads to disease remission, but nearly half of these patients continue to experience sleep disturbances. Those are the findings of a single-center study in the U.S. that also demonstrated that the proportion of Cushing’s patients taking medications for…

A higher volume of epicardial adipose tissue (EAT) — meaning more fat accumulated near the heart muscle and arteries that supply the heart — significantly increases the risk for early heart disease in people with Cushing’s syndrome. That’s according to a study from China that assessed risk factors for left…

The rare case of a 6-month-old girl in India who developed ectopic Cushing’s syndrome due to a cancerous tumor in her right hip was described in a new study. After completing two rounds of chemotherapy and undergoing surgery, the girl recovered normal functioning in her hypothalamic-pituitary-adrenal axis, which controls cortisol…

Women with Cushing’s syndrome may be misdiagnosed with fibromyalgia — a chronic condition characterized by widespread pain and mental distress — despite showing Cushing’s symptoms, a new case series report demonstrates. The researchers say these misdiagnoses of fibromyalgia, occurring in a trio of Cushing’s syndrome patients across three…

Treatment with Isturisa (osilodrostat) is generally well tolerated and effective at reducing cortisol levels and easing Cushing’s disease symptoms in Asian patients, with results similar to those seen in non-Asian patients. That’s according to a new study that compared both patient populations in two Phase 3 clinical trials…

A rare, highly malignant kidney tumor turned out to be the cause of Cushing’s syndrome in an 18-year-old man whose case was described in a recent study. The man had classic symptoms of Cushing’s, including weight gain, fat buildup, and skin changes that resolved after the kidney harboring the…

A new report from researchers at the Montefiore Medical Center in New York details the cases of two women with ectopic Cushing’s secondary to diffuse idiopathic neuroendocrine cell hyperplasia, or DIPNECH — a rare lung disease that may lead to the development of tumors that in extremely rare cases may…

Diagnosing and managing Cushing’s syndrome in children can be complex and takes careful management, according to a case report and review study that described the difficult diagnostic process for a boy who was ultimately found to have Cushing’s disease that could be managed through surgery. “Our case was illustrative…