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A Phase 3 trial testing the oral medication relacorilant in people with Cushing’s syndrome caused by adrenal adenoma, a type of adrenal gland tumor, or adrenal hyperplasia, a condition in which the adrenal glands become enlarged, has finished enrolling participants. Relacorilant’s developer, Corcept Therapeutics, said 137 participants have…

A timely diagnosis of Cushing’s syndrome during pregnancy, along with appropriate individualized treatment, is critical for minimizing complications for the mother and the child, according to a case series study that followed five pregnant women with Cushing’s caused by adrenal tumors at a hospital in China. “By implementing a multidisciplinary…

A 40-year-old man who developed ectopic Cushing’s syndrome as a result of a lung tumor remained undiagnosed for years, despite showing Cushing’s symptoms and progressive physical and mental decline, a recent case study shows. Once he was diagnosed, surgery to remove the tumor resulted in his health improving substantially.

Endoscopic transsphenoidal surgery (ETSS), a type of minimally invasive surgery to remove pituitary tumors through the nose, was found to be safe and effective for bringing about remission in Cushing’s disease, according to a study in Turkey. In patients in whom tumors were larger and had spread into the…

Doctors should suspect Cushing’s syndrome when they see patients with purple stretch marks and metabolic conditions such as diabetes, even if those symptoms aren’t the reasons for a medical visit, physicians in Japan wrote in a case study describing how they reached that diagnosis for a woman in her early…

Individuals with Cushing’s syndrome have a greater buildup of fat around the heart and inside the coronary arteries — the blood vessels that supply blood to the heart — compared with people who don’t have the condition but who are at a higher risk of developing cardiovascular disease, according to…

An interaction between an anti-inflammatory steroid and an anti-fungal medication led to the onset of Cushing’s syndrome and reduced adrenal gland function in a man being treated for complications from a bone marrow transplant. A case report on the 67-year-old man’s symptoms highlights possibly serious consequences from these medicines’…

About 1 in 4 people with Cushing’s syndrome caused by a tumor saw their symptoms come back after undergoing surgery to remove the tumor, a new study found. People with Cushing’s disease, which is caused by a pituitary tumor, saw their tumors recur sooner than did those whose…

Reaching a prompt diagnosis of Cushing’s syndrome and managing it appropriately during pregnancy are critical for minimizing the condition’s harmful effects on the mother and her child, according to case series that followed five women who gave birth at a clinic in Australia. The series also highlighted the challenges of…

A rare adrenal tumor turned out to be the cause of a man’s Cushing’s syndrome, according to a case report from China. The man had severe metabolic complications related to Cushing’s, but these resolved rapidly following surgical removal of the disease-driving tumor, called a pheochromocytoma. Diagnosing and managing a pheochromocytoma…